磷脂双分子层在模型膜和药物传递系统:从物理学到药学

European Pharmaceutical Journal Pub Date : 2021-01-01 DOI:10.2478/afpuc-2021-0008

D. Uhríková

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引用次数: 0

摘要

摘要脂质在水性环境中自发聚集，形成各种结构的超分子结构，称为液晶中间相。它们的热力学性质由双极性/非极性决定，再加上调节结构参数、相几何形状和稳定性的可能性，对药物递送系统的应用具有挑战性。我们回顾了脂质双层功能的几个例子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Phospholipid bilayers in model membranes and drug delivery systems: from physics to pharmacy

Abstract Lipids spontaneously aggregate in an aqueous environment forming supramolecular structures of various architectures known as liquid crystalline mesophases. Their thermodynamic properties determined by dual polar/apolar nature coupled with the possibility to modulate the structural parameters, phase geometry and stability are challenging for applications in drug delivery systems. We review a few examples of functionality of lipid bilayers.

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来源期刊

European Pharmaceutical Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

0.60

自引率

0.00%

发文量

期刊介绍： European Pharmaceutical Journal publishes only original articles not previously published and articles that are not being considered or have not been submitted for publication elsewhere. If parts of the results have been published as conference abstract or elsewhere, it should be stated in references. The ethical standards of the Helsinki-Tokio Declaration should be kept. This should be mentioned in the Methods of manuscript. Reviews are published only on request. Authors, whose submitted research work was performed with the support of a company, should indicate this in Conflict of Interest.