重复经颅磁刺激(rTMS)减少赌博障碍患者的赌博渴望:对高级临床研究的呼吁

Q3 Medicine

NeuroRegulation Pub Date : 2021-03-29 DOI:10.15540/NR.8.1.69

C. Okechukwu

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引用次数: 1

摘要

赌博障碍（GD）是一种成瘾性行为障碍，它会改变额纹状体神经回路和前额叶对奖励相关大脑区域的控制。前额叶皮层和中边缘奖赏通路之间的侵入被认为是GD发病机制背后的主要机制。重复经颅磁刺激（rTMS）是一种利用磁场刺激与情绪和行为控制相关的神经细胞的非侵入性治疗方法；这种刺激通常施加在大脑背外侧前额叶皮层的左侧或右侧。rTMS选择性地调节大脑回路的活动，并具有推翻与GD病理生理学相关的大脑神经回路改变的能力。rTMS调节冲动性、认知/注意力控制、认知可塑性和决策，这对减少赌博欲望和复发至关重要。然而，需要创新的临床研究来分析和确定rTMS对赌博渴望和停止的影响，使用更大的样本量。

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Repetitive Transcranial Magnetic Stimulation (rTMS) for Decreasing Gambling Craving in Patients with Gambling Disorder: A Call for Advanced Clinical Investigations

Gambling disorder (GD) is an addictive behavioral disorder that alters the frontostriatal neural circuitry and prefrontal control of reward-associated brain areas. An intrusion between prefrontal cortex and the mesolimbic reward pathway has been proposed as the major mechanism behind the pathogenesis of GD. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive treatment that utilizes magnetic fields to stimulate nerve cells linked to mood and behavioral control; this stimulation is usually applied either on the left or right side of the dorsolateral prefrontal cortex of the brain. rTMS selectively modulates the activities of brain circuits and possess the ability to overturn the alterations in the neurocircuitry of the brain linked to the pathophysiology of GD. rTMS adjusts impulsivity, cognitive/attentional control, cognitive plasticity, and decision-making, which are crucial in decreasing gambling craving and relapse. However, innovative clinical investigations are needed to analyze and establish the impact of rTMS on gambling craving and cessation, using a larger sample size.

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来源期刊

NeuroRegulation Medicine-Psychiatry and Mental Health

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

19 weeks

期刊介绍： NeuroRegulation is a peer-reviewed journal providing an integrated, multidisciplinary perspective on clinically relevant research, treatment, reviews, and public policy for neuroregulation and neurotherapy. NeuroRegulation publishes important findings in these fields with a focus on electroencephalography (EEG), neurofeedback (EEG biofeedback), quantitative electroencephalography (qEEG), psychophysiology, biofeedback, heart rate variability, photobiomodulation, repetitive Transcranial Magnetic Simulation (rTMS) and transcranial Direct Current Stimulation (tDCS); with a focus on treatment of psychiatric, mind-body, and neurological disorders. In addition to research findings and reviews, it is important to stress that publication of case reports is always useful in furthering the advancement of an intervention for both clinical and normative functioning. We strive for high quality and interesting empirical topics presented in a rigorous and scholarly manner. The journal draws from expertise inside and outside of the International Society for Neurofeedback & Research (ISNR) to deliver material which integrates the diverse aspects of the field, to include: *basic science *clinical aspects *treatment evaluation *philosophy *training and certification issues *technology and equipment