{"title":"镰状细胞肾病。","authors":"R. Falk, J. Jennette","doi":"10.32388/lwugp5","DOIUrl":null,"url":null,"abstract":"Herrick [1] was the first to discover sickle cell hemoglobin ( 2 2) with sickle-shaped erythrocytes. In 1910, he described the case of a young black student from the West Indies with severe anemia characterized by “peculiar elongated and sickle-shaped red blood corpuscles.” Herrick also noted a slightly increased volume of urine of low specific gravity and thus observed the most frequent feature of sickle cell nephropathy: inability of the kidney to concentrate urine normally. L.W. Statius van Eps","PeriodicalId":75446,"journal":{"name":"Advances in nephrology from the Necker Hospital","volume":"23 1","pages":"133-47"},"PeriodicalIF":0.0000,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"26","resultStr":"{\"title\":\"Sickle cell nephropathy.\",\"authors\":\"R. Falk, J. Jennette\",\"doi\":\"10.32388/lwugp5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Herrick [1] was the first to discover sickle cell hemoglobin ( 2 2) with sickle-shaped erythrocytes. In 1910, he described the case of a young black student from the West Indies with severe anemia characterized by “peculiar elongated and sickle-shaped red blood corpuscles.” Herrick also noted a slightly increased volume of urine of low specific gravity and thus observed the most frequent feature of sickle cell nephropathy: inability of the kidney to concentrate urine normally. L.W. Statius van Eps\",\"PeriodicalId\":75446,\"journal\":{\"name\":\"Advances in nephrology from the Necker Hospital\",\"volume\":\"23 1\",\"pages\":\"133-47\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-02-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"26\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in nephrology from the Necker Hospital\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32388/lwugp5\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in nephrology from the Necker Hospital","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32388/lwugp5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 26
摘要
Herrick[1]是第一个发现镰状红细胞的镰状细胞血红蛋白（2 2）的人。1910年，他描述了一名来自西印度群岛的年轻黑人学生患有严重贫血的病例，其特征是“特殊的细长镰刀状红细胞”。赫里克还注意到低比重尿液量略有增加，因此观察到镰状细胞肾病最常见的特征：肾脏无法正常浓缩尿液。L.W.Statius van Eps
Herrick [1] was the first to discover sickle cell hemoglobin ( 2 2) with sickle-shaped erythrocytes. In 1910, he described the case of a young black student from the West Indies with severe anemia characterized by “peculiar elongated and sickle-shaped red blood corpuscles.” Herrick also noted a slightly increased volume of urine of low specific gravity and thus observed the most frequent feature of sickle cell nephropathy: inability of the kidney to concentrate urine normally. L.W. Statius van Eps
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
