{"title":"大麻:大麻和大麻素的治疗用途","authors":"J. Silva, Félix Carvalho","doi":"10.54108/10032","DOIUrl":null,"url":null,"abstract":"Cannabinoids mainly target the endocannabinoid system, which emerges as a potentially interesting\ntherapeutical target due to its major role in modulating key biological processes throughout the\nbody. As such, cannabinoids have already been proposed as, for example, anti-emetics, antispasticity\nagents, appetite stimulants, anti-epileptic, analgesic, depressants of intraocular pressure\nor as agents to control movement disorders in Tourette syndrome.\nHere, we reviewed the research evidence available regarding the use of cannabis and cannabinoids\nfor a set of suggested therapeutical applications, and addressed some of the short- and long-term\nrisks that have been correlated with the use of these substances.\nWe found scarce scientific evidence supporting the use of cannabis-based products for most of\nthe suggested applications, as well as no unmet medical need that is not already tackled by existing\nmedicines (some cannabinoid-based) in the market. In such a scenario, the potential risks associated\nwith the chronic use of these substances may deter their medical use.","PeriodicalId":38489,"journal":{"name":"Revista Espanola de Drogodependencias","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The therapeutic use of cannabis and cannabinoids\",\"authors\":\"J. Silva, Félix Carvalho\",\"doi\":\"10.54108/10032\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cannabinoids mainly target the endocannabinoid system, which emerges as a potentially interesting\\ntherapeutical target due to its major role in modulating key biological processes throughout the\\nbody. As such, cannabinoids have already been proposed as, for example, anti-emetics, antispasticity\\nagents, appetite stimulants, anti-epileptic, analgesic, depressants of intraocular pressure\\nor as agents to control movement disorders in Tourette syndrome.\\nHere, we reviewed the research evidence available regarding the use of cannabis and cannabinoids\\nfor a set of suggested therapeutical applications, and addressed some of the short- and long-term\\nrisks that have been correlated with the use of these substances.\\nWe found scarce scientific evidence supporting the use of cannabis-based products for most of\\nthe suggested applications, as well as no unmet medical need that is not already tackled by existing\\nmedicines (some cannabinoid-based) in the market. In such a scenario, the potential risks associated\\nwith the chronic use of these substances may deter their medical use.\",\"PeriodicalId\":38489,\"journal\":{\"name\":\"Revista Espanola de Drogodependencias\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Espanola de Drogodependencias\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.54108/10032\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Espanola de Drogodependencias","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.54108/10032","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Cannabinoids mainly target the endocannabinoid system, which emerges as a potentially interesting
therapeutical target due to its major role in modulating key biological processes throughout the
body. As such, cannabinoids have already been proposed as, for example, anti-emetics, antispasticity
agents, appetite stimulants, anti-epileptic, analgesic, depressants of intraocular pressure
or as agents to control movement disorders in Tourette syndrome.
Here, we reviewed the research evidence available regarding the use of cannabis and cannabinoids
for a set of suggested therapeutical applications, and addressed some of the short- and long-term
risks that have been correlated with the use of these substances.
We found scarce scientific evidence supporting the use of cannabis-based products for most of
the suggested applications, as well as no unmet medical need that is not already tackled by existing
medicines (some cannabinoid-based) in the market. In such a scenario, the potential risks associated
with the chronic use of these substances may deter their medical use.