21世纪的MALDI-TOF质谱

Q4 Biochemistry, Genetics and Molecular Biology

Biochemist Pub Date : 2022-10-27 DOI:10.1042/bio_2022_130

M. E. Dueñas, Matthias Trost

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引用次数: 1

摘要

今年是田中光一（Koichi Tanaka）获得诺贝尔化学奖20周年，该奖与约翰·芬恩（John Fenn）和库尔特·维特里希（Kurt Wüthrich）共同获得，因为他展示了激光技术在分析生物大分子方面的适用性。激光解吸原理是当今许多分析方法的基础，如基质辅助激光解吸/电离（MALDI）。在这篇文章中，我们对MALDI进行了概述，并强调了其在生物化学界的威力、多功能性和应用范围。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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MALDI-TOF mass spectrometry in the 21st century

This year marks the 20th anniversary of Koichi Tanaka securing the Nobel Prize in chemistry, shared with John Fenn and Kurt Wüthrich, for demonstrating the applicability of laser technology to analyze biological macromolecules. The principle of laser desorption is fundamental for many of today’s analytical methods such as matrix-assisted laser desorption/ionization (MALDI). In this article, we provide an overview of MALDI and highlight the power, versatility and range of applications within the biochemistry community.

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来源期刊

Biochemist Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

1.20

自引率

0.00%

发文量

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