评估多发性硬化症患者下肢运动强度域的不对称性:一项初步研究

J. W. Farrell, Shelby R. Shipman, Christopher D. Black, C. Ade, Rebecca D. Larson
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引用次数: 0

摘要

多发性硬化症(PwMS)患者会经历各种各样的身体损伤,这些损伤可能以不对称的方式呈现,导致对侧肢体之间存在显著差异(即bbb10 %)。PwMS的不对称与行走障碍和姿势不稳定有关。运动强度已被证明会影响健康人群不对称结果的程度,并可能对适当的运动处方产生影响。目前的初步研究的目的是调查在PwMS单腿骑行期间划定运动强度域的代谢事件中可能存在的不对称性。5名PwMS(扩展残疾状态量表范围2.0至4.5)完成了单腿增量循环测试(SLICT)和一系列单腿恒定功率至衰竭时间试验,以确定双下肢的气体交换阈值(GET)、峰值耗氧量(VO2peak)、峰值输出功率(PPO)、临界功率(CP)和W ' (CP以上的运动耐量)。统计分析显示,VO2peak、GET、CP、PPO和W′在肢体间无显著差异。只有W′不对称评分显著(49.5±28.7∶10.0,p = 0.04)大于10%。GET、CP和PPO的不对称评分之间没有显著差异。目前的试点调查结果表明,运动强度可能不会影响PwMS的不对称性结果。未来需要更大样本量和更高残疾水平的研究来充分了解运动强度对PwMS不对称性的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessing Asymmetry in Exercise Intensity Domains between Lower Limbs in Persons with Multiple Sclerosis: A Pilot Study
Persons with multiple sclerosis (PwMS) experience a variety of physical impairments that can present in an asymmetrical pattern, resulting in significant differences between contralateral limbs (i.e., >10%). Asymmetries in PwMS have been associated with walking impairment and postural instability. Exercise intensity has been shown to influence the degree of asymmetry outcomes in healthy populations, and may have an impact on appropriate exercise prescriptions. The purpose of the current pilot study was to investigate the potential presence of asymmetry in metabolic events demarcating exercise intensity domains during single-leg cycling in PwMS. Five PwMS (Expanded Disability Status Scale range 2.0 to 4.5) completed a single leg incremental cycling test (SLICT) and a series of single-leg constant power time-to-exhaustion trials to determine gas exchange threshold (GET), peak oxygen consumption (VO2peak), peak power output (PPO), critical power (CP), and W’ (exercise tolerance above CP) for both lower limbs. Statistical analysis revealed no significant between-limb differences for VO2peak, GET, CP, PPO, and W’. Only W’ asymmetry score was significantly (49.5 ± 28.7 vs. 10.0, p = 0.04) greater than 10%. No significant differences between asymmetry scores at the GET, CP, and PPO were observed. Results from the current pilot investigation suggest that exercise intensity may not influence asymmetry outcomes in PwMS. Future studies with larger sample sizes and those with higher disability levels are required to fully understand the influence of exercise intensity on asymmetry in PwMS.
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