结直肠癌腹膜癌病变的18F-FDG PET/CT影像表现及临床意义

中华核医学与分子影像杂志 Pub Date : 2019-11-25 DOI:10.3760/CMA.J.ISSN.2095-2848.2019.11.003

Sun Chunfeng, Tang Zhonghua, G. Yan, Zhu Jianwei, M. Xiaoying, Ge Chengchun, Bao Shanlei

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引用次数: 1

摘要

目的分析结直肠癌腹膜癌(PC)患者的18f -氟脱氧葡萄糖(FDG) PET/CT影像学表现，探讨其临床意义。方法2016年5月~ 2018年8月收治46例患者，其中男25例，女21例;回顾性分析在南通大学附属医院行18F-FDG PET/CT显像并有完整临床资料的结直肠癌PC患者，年龄36-82岁(62.0±10.4)岁。采用腹膜癌指数(PCI)分级系统对PC病变进行评价。数据分析采用独立样本t检验和Kruskal-Wallis H检验。结果46例患者均有不同的PC CT表现，PET上均观察到FDG代谢。根据原发性结直肠癌病变的部位将患者分为不同的组。左结肠组PC病变直径为(2.46±1.26)cm，与直肠组((3.19±1.72)cm;t=-2.77, P 0.05)。10例患者有腹腔和盆腔积液。结论18F-FDG PET/CT能很好地显示结直肠癌患者的PC, PCI联合18F-FDG PET/CT对PC的诊断和治疗具有重要作用。关键词:结直肠肿瘤;肿瘤转移;腹膜;正电子发射断层扫描;断层扫描，x射线计算机;脱氧葡萄糖

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18F-FDG PET/CT imaging manifestations of peritoneal carcinomatosis from colorectal cancer and its clinical significance

Objective To analyze 18F-fluorodeoxyglucose(FDG) PET/CT imaging manifestations in patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) and investigate its clinical significance. Methods From May 2016 to August 2018, 46 patients (25 males, 21 females; age range: 36-82(62.0±10.4) years) with PC from CRC who underwent 18F-FDG PET/CT imaging in Affiliated Hospital of Nantong University and had complete clinical data were retrospectively analyzed. The peritoneal carcinomatosis index (PCI) grading system was used to evaluate the PC lesions. Independent-sample t test and Kruskal-Wallis H test were used for data analysis. Results There were various CT manifestations of PC, while FDG metabolism on PET was observed in all 46 patients. Patients were divided into different groups according to the location of the primary CRC lesion. The diameter of PC lesion in the left colon group was (2.46±1.26) cm, which was significantly different from that of the rectum group ((3.19±1.72) cm; t=-2.77, P 0.05). Ten patients had abdominal and pelvic effusion. Conclusion 18F-FDG PET/CT can well display the PC in patients with CRC, and the combination of PCI and 18F-FDG PET/CT plays an important role in the diagnosis and treatment of PC. Key words: Colorectal neoplasms; Neoplasm metastasis; Peritoneum; Positron-emission tomography; Tomography, X-ray computed; Deoxyglucose

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来源期刊

中华核医学与分子影像杂志核医学，分子影像

自引率

0.00%

发文量

5088

期刊介绍： Chinese Journal of Nuclear Medicine and Molecular Imaging (CJNMMI) was established in 1981, with the name of Chinese Journal of Nuclear Medicine, and renamed in 2012. As the specialized periodical in the domain of nuclear medicine in China, the aim of Chinese Journal of Nuclear Medicine and Molecular Imaging is to develop nuclear medicine sciences, push forward nuclear medicine education and basic construction, foster qualified personnel training and academic exchanges, and popularize related knowledge and raising public awareness. Topics of interest for Chinese Journal of Nuclear Medicine and Molecular Imaging include: -Research and commentary on nuclear medicine and molecular imaging with significant implications for disease diagnosis and treatment -Investigative studies of heart, brain imaging and tumor positioning -Perspectives and reviews on research topics that discuss the implications of findings from the basic science and clinical practice of nuclear medicine and molecular imaging - Nuclear medicine education and personnel training - Topics of interest for nuclear medicine and molecular imaging include subject coverage diseases such as cardiovascular diseases, cancer, Alzheimer’s disease, and Parkinson’s disease, and also radionuclide therapy, radiomics, molecular probes and related translational research.