在无侧限压缩和探测方案中表征肾脏和肝脏的材料特性,特别参考变应变速率

Blake Johnson, Scott Campbell, Naira Campbell-Kyureghyan
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引用次数: 5

摘要

肝脏和肾脏是由于施加在腹部的创伤冲击力而最常见的损伤器官,由于难以诊断内出血的风险,这对医生来说是一个挑战。更好地了解损伤的机制将改善诊断、治疗、法医学和其他领域。有限元建模是一种有助于理解这一点的工具,但需要准确的材料特性,包括应变率依赖性和使用动物组织特性而不是人类特性的可行性。在不同应变率下,对来自人和猪标本的肝和肾组织都发现了探测方案中的弹性模量以及压缩方案中的弹模、失效应力和失效应变。当比较无侧限压缩和探测方案时,人类肾脏和肝脏的弹性模量都有所增加,但仅猪肾的弹性模量有所增加。发现肝脏和肾脏特性的应变速率依赖性,并且观察到在失效应力比弹性模量更高的速率下具有更大的饱和效应。总体而言,对完整肝脏和肾脏的材料特性进行了表征,并对应变率依赖性进行了数值模拟。研究结果表明,一些肾脏和肝脏材料的特性因人类和猪的组织而异。因此,在人类肝脏和肾脏的计算或物理模型中使用猪组织的材料特性并不总是合适的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Characterizing the Material Properties of the Kidney and Liver in Unconfined Compression and Probing Protocols with Special Reference to Varying Strain Rate
The liver and kidneys are the most commonly injured organs due to traumatic impact forces applied to the abdomen and pose a challenge to physicians due to a hard-to-diagnose risk of internal bleeding. A better understanding of the mechanism of injury will improve diagnosis, treatment, forensics, and other fields. Finite element modelling is a tool that can aid in this understanding, but accurate material properties are required including the strain rate dependency and the feasibility of using animal tissue properties instead of human. The elastic modulus in a probing protocol and the elastic modulus, failure stress, and failure strain in a compression protocol were found for both liver and kidney tissue from human and porcine specimens at varying strain rates. Increases in the elastic modulus were seen for both the human kidney and liver, but only for the porcine kidney, when comparing the unconfined compression and probing protocols. A strain rate dependency was found for both the liver and kidney properties and was observed to have a larger saturation effect at higher rates for the failure stress than for the elastic modulus. Overall, the material properties of intact liver and kidney were characterized, and the strain rate dependency was numerically modelled. The study findings suggest that some kidney and liver material properties vary from human to porcine tissue. Therefore, it is not always appropriate to use material properties of porcine tissue in computational or physical models of the human liver and kidney.
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