孤立性卵巢浆细胞瘤:髓外浆细胞瘤的罕见定位。案例报告

Salma Fares, Adil Taoufik, A. Maataoui, Kaoutar Sokori, O. Qamouss
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引用次数: 1

摘要

背景:孤立性浆细胞瘤是一种罕见的浆细胞恶性肿瘤,占所有浆细胞异常的5-10%,髓外浆细胞瘤占3-5%。它们在女性生殖道中的定位非常罕见,无论是作为孤立性浆细胞瘤还是作为播散性MM的一部分。孤立性卵巢浆细胞瘤极为罕见。病例:一位52岁的女性,表现为绝经后复发性子宫出血,伴有左侧卵巢肿块。她被诊断为孤立性卵巢浆细胞瘤,无系统疾病。该患者接受了完整的手术切除,并进行了全面的检查,以排除多发性骨髓瘤,目的是获得一种小血清单克隆蛋白,该蛋白在术后已消退。在17个月的随访中,患者仍然活着,表现良好,没有复发或进展为多发性骨髓瘤的迹象。卵巢孤立性浆细胞瘤虽然罕见,但可在没有任何明显症状或实验室异常检查的情况下发生,由于其复发或进展为MM,需要及时、充分的治疗和严格的监测。完全手术切除后积极监测是合适的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Solitary Ovarian Plasmocytoma: A Rare localization of Extramedullary Plasmocytoma. A Case Report
Background: Solitary plasmacytoma is a rare malignant neoplasm of plasma cells accounting 5-10% of all plasma cell dyscrasias with extramedullary plasmocytoma in 3- 5%. Their localization in the female genital tract is quite rare, either as solitary plasmacytomas or as part of a disseminated MM. Solitary ovarian plasmocytoma is extremely rare. Case: A 52-year-old woman, presented presented postmenopausal recurring episodes of metrorrhagia with left ovarian mass. She was diagnosed with solitary ovarianplasmocytoma without systemicdisease. The patient underwent complete surgery resection and a full work up to rule out multiple myeloma that objectived a small serum monoclonal protein that had resolved postoperatively. At 17 months of follow-up, the patient is still alive and doing well with no signs of recurrence or progression to mutliple myeloma. Although rare, solitary plasmacytoma of the ovary can occur without any overt symptoms or laboratory abnormalities tests and require prompt and adequate treatment and rigorous monitoring due to their ability to relapse or progress to MM. Complete surgical resection followed by activesurveillance is appropriate.
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