卵巢癌手术后营养缺乏症的纠正:一个临床病例

L. I. Bashirova, A. Safonov, R. R. Kamilova, D. Lipatov, A. Bakirov, A. Samorodov
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引用次数: 0

摘要

背景根据一些研究,在卵巢癌症和其他妇科恶性肿瘤中,营养缺乏的患病率超过70%,因此构成了术后死亡率、手术并发症和住院时间延长的重要风险因素。因此,有效的营养缺乏纠正方法有助于改善卵巢癌症的预后,尤其是在接受激进手术干预的患者中。文献中出现了新的系统证据,证明这种新方法对变异类别患者的危重状态的影响。同时,这些证据仅具有推荐价值,没有假设营养缺乏管理的现行标准或方案。这个问题目前仍然悬而未决,需要认真研究和分析。材料和方法。该临床病例证明了营养缺乏矫正在癌症卵巢患者个体化根治性手术后的疗效。结果和讨论。第1天供应的能量>42%,第3天供应的能源>83%,并且在强化治疗的第7天达到了目标值。营养缺乏标志物动态显示,早在手术后第3天,转铁蛋白、甘油三酯和外周血淋巴细胞计数就有所增长。白蛋白是最新的反应,仅在第7天增加。结论:新营养策略的引入及其影响的知识取决于进一步的高质量研究,尤其是前瞻性研究,包括更大的干预类型和临床结果的同质性,以及更广泛的女性卵巢癌症样本。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nutrient Deficiency Correction in Ovarian Cancer Patients Following Surgical Treatment: a Clinical Case
Background. According to some studies, nutrient deficiencies reach an over-70% prevalence in ovarian cancer, among other gynaecological malignancies, thus constituting an important risk factor for postoperative mortality, surgical complications and longer hospital stays. Therefore, effective nutrient deficiency correction methods are warranted to improve the ovarian cancer outcomes, especially in patients following radical surgical interventions. New systematic evidence emerges in literature on the impact of such novel methods on the critical status of variant-category patients. Meanwhile, such evidence bears a recommendatory value only, with no current standard or protocol assumed for nutrient deficiency management. This issue presently remains open and requires careful research and analysis.Materials and methods. The clinical case demonstrates the efficacy of nutrient deficiency correction in an ovarian cancer patient following an individualised radical surgery.Results and discussion. The energy supplied on day 1 was >42%, >83% on day 3, and the target values had been achieved by day 7 of intensive therapy. The nutrient deficiency marker dynamics revealed the growth of transferrin, triglycerides and peripheral blood lymphocyte counts as early as by day 3 post-surgery. Albumin was the latest to respond, increasing only on day 7.Conclusion. The introduction of novel nutrition strategies and knowledge of their impact depend on further high-quality research, especially prospective studies, incorporating a  greater homogeneity of intervention types and clinical outcomes, as well as wider sampling of female ovarian cancer. 
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