白桦乳膏对乳腺癌患者皮肤辐射反应的影响初步临床试验

Q4 Pharmacology, Toxicology and Pharmaceutics
J. Salamzadeh, M. Kamalinejad, B. Mofid, S. Mortazavi, Alireza Sheikhlar, M. Babaeian
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引用次数: 3

摘要

放射治疗是消灭乳腺癌的一种非常有效的方法,但会对皮肤产生不良影响。已经进行了大量的研究,以找到一种方法来减轻或减轻辐射对皮肤的不良影响。本研究的目的是观察白桦乳膏治疗放疗性乳腺癌患者皮肤损伤的临床效果。在一项双盲随机研究中,对32例不同阶段的放疗引起的皮肤反应进行了评估;治疗组16例采用荷叶榆乳膏,对照组16例。治疗2周后,与安慰剂组相比,黄菖蒲组患者的皮肤反应等级明显降低。经2周治疗后,白茱萸组患者对皮肤干燥、瘙痒、疼痛、灼烧、水疱、溃疡的态度均有明显改善。刺叶参乳膏可有效减轻放射治疗引起的皮肤损伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effect of Elaeagnus angustifolia L. Cream on Radiation-Induced Skin Reactions in Women with Breast Cancer; A Preliminary Clinical Trial
Radiotherapy, a highly effective way to destroy breast cancer, causes skin adverse effects. A considerable amount of studies have been conducted to find a way to alleviate or relieve dermal adverse effects of radiation. The aim of this study was to observe the clinical effect of Elaeagnus angustifolia L. cream to treat radiotherapy-induced skin destruction in breast cancer patients. thirty two patients suffering from different stages of radiotherapy-induced skin reactions were evaluated in a double-blind randomized study; 16 patients in the treatment group received Elaeagnus angustifolia cream, while the other 16 patients, served as control group. Two weeks after the treatment, patients in Elaeagnus angustifolia group showed significantly lower skin reaction grade compared with placebo group. The attitude of the patients of Elaeagnus angustifolia group about dryness, itching, pain, burning, blisters and sores was significantly improved after two weeks of treatment. Elaeagnus angustifolia cream may effectively reduce the radiotherapy-induced dermal injury.
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来源期刊
Iranian Journal of Pharmaceutical Sciences
Iranian Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
0.50
自引率
0.00%
发文量
0
期刊介绍: Iranian Journal of Pharmaceutical Sciences (IJPS) is an open access, internationally peer-reviewed journal that seeks to publish research articles in different pharmaceutical sciences subdivisions: pharmacology and toxicology, nanotechnology, pharmaceutics, natural products, biotechnology, pharmaceutical chemistry, clinical pharmacy and other pharmacy related topics. Each issue of the journal contents 16 outstanding research articles in area of pharmaceutical sciences plus an editorial written by the IJPS editors on one of the most up to date advances topics in pharmacy. All articles published by IJPS would be permanently accessible online freely without any subscription charges. Authors of the published articles have granted the right to use and disseminate their article to third parties.
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