Mechanisms of Plasmid Replication

Plasmids are small, circular extra fragments of DNA, commonly found in bacteria that are capable of replicating independent of the host genome, though plasmids are not required for survival of a living organism. But encodes essential genetic determinants that enable an organism to adapt and resist unfavourable conditions for better survival. Rolling circle, Col E1 type and iteron-containing replicons are the common modes through which plasmid replicates, each mechanism with unique significance to the organism.