橄榄叶对血压的影响;系统综述和荟萃分析

IF 0.2 Q4 UROLOGY & NEPHROLOGY
A. Fatahian, S. Yousefi, M. Azadbakht, M. Moosazadeh, M. Fakhri
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引用次数: 0

摘要

背景:高血压已被确定为世界第三大死亡原因。与抗高血压药物相比,药用植物具有成本效益且无不良反应,因此在大多数国家都很受欢迎。橄榄叶就是其中一种植物。因此,当前系统综述和荟萃分析的目的是确定食用橄榄叶对收缩压和舒张压的影响。证据获取:为了检索相关研究,检索了以下国内外数据库:PubMed、Scopus、Web of Science、Embase、Cochrane、ProQuest和Google Scholar搜索引擎、ClinicalTrials.gov协议注册和结果系统(PRS)、BioMed Central管理的ISRCTN注册中心,以及世界卫生组织(世界卫生组织)国际临床试验注册平台。使用STATA软件(版本14)对收集的数据进行分析,显著性水平为P<0.05。结果:在五项样本量为145人(平均年龄范围为33.30±5.25岁)的研究中,食用橄榄叶对收缩压[0.87(95%CI:1.09,-0.64)]和舒张压[0.39(95%CI:0.57,-0.21)]有显著影响。食用橄榄叶还降低了胆固醇水平[0.52(95%CI:-0.81,-0.22)]、低密度脂蛋白(LDL-c)水平[0.35(95%CI:-0.58,-0.12)]和甘油三酯水平-0.67(95%CI:-1.19,-0.16)]。尽管如此,橄榄叶对降低高密度脂蛋白水平没有统计学意义。结论:我们观察到食用橄榄叶可显著降低收缩压和舒张压、胆固醇、甘油三酯和LDL-的水平。注册:目前的协议也在PROSPERO上注册(ID:221277,日期:2022年4月16日)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effect of olive leaf use on blood pressure; A systematic review and meta-analysis
Context: Hypertension has been identified as the world’s third leading cause of death. Due to their cost-effectiveness and lack of adverse effects compared to antihypertensive medications, medicinal plants have gained popularity in most countries. The olive leaf is one of these plants. As a result, the purpose of the current systematic review and meta-analysis was to determine the effect of olive leaf consumption on systolic and diastolic blood pressure. Evidence acquisition: The following domestic and international databases were searched in order to retrieve relevant studies: PubMed, Scopus, Web of Science, Embase, Cochrane, ProQuest, and Google Scholar search engine, the ClinicalTrials.gov Protocol Registration and Results System (PRS), the ISRCTN registry administered by BioMed Central, and the World Health Organization’s (WHO) International Clinical Trials Registry Platform. The data collected were analyzed using STATA software (version14) at a significance level of P<0.05. Results: Olive leaf consumption had a significant effect on systolic blood pressure [-0.87 (95% CI: -1.09, -0.64)] and diastolic blood pressure [-0.39 (95% CI: -0.57, -0.21)] in five studies with a sample size of 145 people (mean age range of 33.30 ± 5.25 years). Consumption of olive leaves also decreased cholesterol levels [-0.52 (95% CI: -0.81, -0.22)], low-density lipoprotein (LDL-c) levels [-0.35 (95% CI: -0.58, -0.12)], and triglycerides levels [-0.67 (95% CI: -1.19, -0.16)]. Nonetheless, the olive leaf had no statistically significant effect on reducing highdensity lipoprotein levels. Conclusion: We observed that olive leaf consumption significantly reduced the levels of systolic and diastolic blood pressure, cholesterol, triglycerides, and LDL-c. Registration: The current protocol was also registered on PROSPERO (ID: 221277, Date: 16.04.2022).
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来源期刊
Journal of Renal Injury Prevention
Journal of Renal Injury Prevention UROLOGY & NEPHROLOGY-
CiteScore
1.60
自引率
0.00%
发文量
36
期刊介绍: The Journal of Renal Injury Prevention (JRIP) is a quarterly peer-reviewed international journal devoted to the promotion of early diagnosis and prevention of renal diseases. It publishes in March, June, September and December of each year. It has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views and renal biopsy teaching point. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of renal failure and modalities in the treatment of diabetic nephropathy. A further aim of this journal is to emphasize and strengthen the link between renal pathologists/nephropathologists and nephrologists. In addition, JRIP welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical nephrology. Futuristic conceptual hypothesis that integrate various fields of acute kidney injury and renal tubular cell protection are encouraged to be submitted.
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