Chemical composition and biological activity of Zosima absinthifolia (apiaceae)

Zosima absinthifolia (Vent.) Link is a perennial herb and is found in Iran, Turkey, Iraq and different countries of the Caucasus, Middle East and Central Asia. It is the only member of Zosima genus growing in Azerbaijan. It has been used as a medicinal plant since ancient time in Iran, Turkey and Pakistan. The fruits are used as a food flavoring and as a food spice in Iran. The knowledge of Z. absinthifolia organs containing a great number of bioactive compounds is of high importance. The aim of this study is to sum up literature data on the results of experimental studies of the chemical composition and biological activity of Z. absinthifolia. The results of the chemical study of Z. absinthifolia show that fruits, roots, seeds, flowers and other aboveground parts of plants are rich in various biologically active substances such as coumarins, furocoumarins, pyranocoumarins, flavonoids, monoterpenes, sesquiterpenes and etc. Chemical components that isolated from different organs of Z. absinthifolia have allelopathic, high antibacterial, antifungal, antioxidant, anti-inflammatory and other properties. Some of the chemical constituents have substantial pharmacological properties. It is clear that Z. absinthifolia has significant potential for useful natural supplements in many contemporary diseases.