Talisapatradi和Vyoshadi choorna含片的开发和评价:一种阿育吠陀传统配方

IF 0.7 Q4 PHARMACOLOGY & PHARMACY
Manas Sahoo, Umashankar Srinivasan, R. Varier
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引用次数: 1

摘要

在阿育吠陀,Talisapatadi-choorna(TPC)和Vyoshadi choorna(VSC)是治疗咳嗽、感冒、哮喘和鼻炎的常用药物。这些症状主要是由病毒引起的上呼吸道感染引起的。目前,除了滥用抗生素、局部麻醉剂和止痛药外,没有有效的药物。TPC和VSC的传统配方难以管理,因此开发了一种易于制造的含片配方。通过初步薄层色谱(TLC)衍生化研究进行了植物化学分析。高效薄层色谱(HPTLC)分析证实含片配方中存在草药活性成分。TLC分析结果表明,TPC和VSC含有黄酮类、甾类和植物甾醇类植物化学物质以及生物碱家族。发现草药活性物质在最终制剂中是稳定的,不会对制剂中使用的赋形剂产生任何干扰。由TPC和VSC配制的含片被发现是传统阿育吠陀制剂传统形式的有前途的替代品。采用傅立叶变换红外光谱法和高效薄层色谱法进行了相容性研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Development and evaluation of Talisapatradi and Vyoshadi choorna lozenges: An ayurvedic traditional formulation
In Ayurveda, Talisapatradi choorna (TPC) and Vyoshadi choorna (VSC) are commonly used medicines for cough, cold, asthma, and rhinitis. These symptoms are due to upper respiratory infections of predominantly of viral origin. Currently, there are no effective medicines except indiscriminate uses of antibiotics, local anesthetics, and pain killers. The conventional formulation of TPC and VSC is difficult to administer so an easy manufacturing lozenge formulation was developed. The phytochemical analysis was done by preliminary thin layer chromatography (TLC) derivatization studies. High-performance thin layer chromatography (HPTLC) analysis confirmed the presence of herbal actives in the lozenge formulations. The TLC analysis results showed that TPC and VSC contain phytochemicals of flavonoids, steroids and phytosterols, and alkaloids family. The herbal actives were found to be stable in the final formulation without any interference with the excipients used in the formulation. The lozenges formulated from TPC and VSC are found to be promising alternatives to traditional form for the traditional Ayurvedic preparation. Compatibility study was done using Fourier transform infrared spectroscopy and HPTLC study.
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来源期刊
Journal of Reports in Pharmaceutical Sciences
Journal of Reports in Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.40
自引率
0.00%
发文量
0
期刊介绍: The Journal of Reports in Pharmaceutical Sciences(JRPS) is a biannually peer-reviewed multi-disciplinary pharmaceutical publication to serve as a means for scientific information exchange in the international pharmaceutical forum. It accepts novel findings that contribute to advancement of scientific knowledge in pharmaceutical fields that not published or under consideration for publication anywhere else for publication in JRPS as original research article. all aspects of pharmaceutical sciences consist of medicinal chemistry, molecular modeling, drug design, pharmaceutics, biopharmacy, pharmaceutical nanotechnology, pharmacognosy, natural products, pharmaceutical biotechnology, pharmacology, toxicology and clinical pharmacy.
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