Boundary Layer Effects on Ionic Flows Via Classical Poisson-Nernst-Planck Systems

Abstract A quasi-one-dimensional steady-state Poisson-Nernst-Planck model of two oppositely charged ion species through a membrane channel is analyzed. The model problem is treated as a boundary value problem of a singularly perturbed differential system. Our analysis is based on the geometric singular perturbation theory but, most importantly, on specific structures of this concrete model. The existence and (local ) uniqueness of solutions to the boundary value problem is established. In particular, an approximation of both the individual flux and the I-V (current-voltage) relation are derived explicitly from the zeroth order approximation (in ") solutions, from which the boundary layer effects on ionic flows are studied in great details.