先天性巨大黑色素痣1例报告

Q4 Medicine
M. Alipour, K. Khashei Varnamkhasti, Marzieh Eslami Moghaddam, Masumeh Panahi
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引用次数: 1

摘要

背景:巨大先天性黑色素细胞痣是由子宫内参与丝裂原活化蛋白激酶途径的基因发生体细胞突变引起的。这是一种罕见的黑色素细胞病变,发病率为出生时或出生后不久每20000名活产中就有1名。病例介绍:在这里,我们介绍了一个足月男性新生儿患有巨大先天性黑色素细胞痣的病例。他是一位33岁的母亲所生。最初的儿科检查显示他的躯干有一个皮肤马赛克图案。这个区域的色素沉着和粗糙的皮肤,以及几个明显的疣状病变和界限分明的边界,证实了巨大的先天性黑色素细胞痣。结论:尽管这种病变很罕见,但它具有重要意义,因为它可能会伴随严重的并发症,如恶性黑色素瘤。因此,有必要通过认识病变的性质来采取适当的医疗管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case Report of Giant Congenital Melanocytic Nevus
Background: Giant congenital melanocytic nevus is caused by intrauterine somatic mutations in the genes involved in the mitogen-activated protein kinase pathway. It is a rare melanocytic lesion with a prevalence of 1 per 20,000 live births occurring at birth or shortly thereafter. Case Presentation: Here, we presented the case of a term male neonate with giant congenital melanocytic nevus. He was born to a 33-year-old mother. The initial pediatric examination revealed a skin mosaic pattern in his torso. The pigmented and rough skin of this area, along with several prominent wart-shaped lesions and demarcated borders, confirmed the giant congenital melanocytic nevus. Conclusion: Despite the rarity of this lesion, it is of great importance since it may associate with severe complications, such as malignant melanoma. Therefore, it is necessary to adopt appropriate medical management by recognizing the nature of the lesion.
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来源期刊
CiteScore
0.30
自引率
0.00%
发文量
16
审稿时长
8 weeks
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