评估健康年轻受试者短期“干”浸泡期间自主功能的心率变异性参数

L. Gerasimova-Meigal, A. Meigal, N. Sireneva, Maria Gerasimova, A. Sklyarova
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引用次数: 1

摘要

在短期暴露于使用“干”浸泡的模拟微重力条件下,人类受试者心血管调节的直接机制方面,目前的知识存在差距。目标本研究的目的是在线性和非线性心率变异性和血液动力学参数的帮助下,评估年轻健康受试者在45分钟疗程中的心血管反应。该研究自愿招募了33名年龄在19-23岁之间的受试者(18名男性,15名女性)。后果研究表明,收缩压和舒张压相当稳定,心率变异性的一些时域参数(SDNN、RMSSD、pNN50等)和频域参数(TP、HF、LF,但不是VLF)在45分钟的“干”浸泡过程中显著增加。在心率变异性的非线性参数中,只有ApEn在“干”浸泡过程中显著降低。结论我们的研究结果表明,在年轻健康受试者中,短期45分钟的DI治疗会引发基于压力感受器反射的神经源性自主反应。这为这些受试者在“干”浸泡过程中提供了稳定的血液动力学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Heart Rate Variability Parameters to Evaluate Autonomic Functions in Healthy Young Subjects during Short-Term “Dry” Immersion
There is a gap in the current knowledge on the immediate mechanisms of cardiovascular regulation in human subjects within short-term exposure to modeled microgravity using “dry” immersion. Aim. The purpose of the study was to evaluate cardiovascular responses in young healthy subjects during a 45 min session with the help of linear and nonlinear heart rate variability and hemodynamics parameters. The research voluntarily enrolled 33 subjects (18 men, 15 women) aged 19–23 years old. Results. The study showed that systolic and diastolic blood pressure was quite stable, some time-domain parameters of heart rate variability (SDNN, RMSSD, pNN50, etc.) and the frequency-domain (TP, HF, LF, but not VLF) have significantly increased within a 45 min “dry” immersion session. Of the non-linear parameters of heart rate variability, only ApEn significantly decreased during the “dry” immersion session. Conclusion. Our results suggest that a short-term 45 min DI session provokes in young healthy subjects neurogenic autonomic reaction based on the baroreceptor reflex. This provides stable hemodynamics in these subjects along the “dry” immersion session.
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