肥胖儿童因家庭原因对低碳水化合物生活方式变化的临床表现及反应

IF 0.1 Q4 PEDIATRICS
H. Cakmak, İ. Arslanoğlu, M. Sungur, S. Bolu
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引用次数: 0

摘要

目的:本研究旨在1)确定进入儿科内分泌转诊中心的肥胖儿童的临床状况2)调查在有或没有运动的儿童人群中低碳水化合物饮食的效率和依从性,二甲双胍材料和方法:自2012年1月至2014年8月招募所有肥胖且BMI百分位数>95的受试者。我们对基础回顾性评估,向所有人推荐全家庭低碳水化合物饮食实践和锻炼,并对选定病例推荐二甲双胍,并记录第一、第三、第六和第十二个月的自我报告依从性。结果:36名受试者使用二甲双胍的体重减轻率较高(90.0%,p=0.010),但体重减轻的数量没有差异。160例未使用二甲双胍的患者;根据饮食组和运动组,仅饮食组、仅运动组以及饮食组和锻炼组均显著减轻了体重(OR:12.08,95%CI 3.93-41.66,p<0.001;OR:3.04,95%CI 1.18-7.84,p=0.022;OR:32.80,95%CI 7.14-150.77,p<001)。运动加饮食(95.3%,p=0.002)和单纯饮食(88.9%,p=0.023)甚至比单独运动(65.5%)更有效。在第十二个月,13.8%的患者进行了随访。结论:肥胖在早期阶段会引起代谢并发症。低碳水化合物饮食被证明是可以接受和有用的。长期一致性仍然是一个挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Picture at Attendance and Response to Flexible FamilyBased Low-Carb Life Style Change in Children With Obesity
Aim: The study aims 1) to determine the clinical status of obese children at the admittance to the pediatric endocrinology referral center 2) to investigate the efficiency and compliance of the low-carb diet in a pediatric population with or without exercise, metformin Material and Methods: All subjects with the complaint of obesity and BMI percentile >95 were recruited from January 2012-August 2014. We evaluated basal retrospectively, recommended low carbohydrate family-wide eating practice and exercise to all, and metformin to selected cases, and recorded Self-reported adherence at first, third, sixth, and twelfth months. Results: Thirty-six subjects used metformin with a higher ratio of weight loss (90.0%, p=0.010) without a difference in the number of lost kilograms. In 160 cases without metformin; diet only, exercise only, and both diet and exercise groups lost weight significantly according to neither diet nor exercise group (OR:12.08, 95% CI 3.93-41.66, p<0.001; OR:3.04, 95% CI 1.18-7.84, p=0.022 and OR:32.80, 95% CI 7.14-150.77, p<0.001 respectively). Exercise plus diet (95.3%, p=0,002) and only diet (88.9%, p=0,023) were even more efficient than exercise alone (65.5%). In the twelfth month, 13.8% were on follow-up. Conclusion: Obesity gives rise to metabolic complications in the very early stages. A low carbohydrate diet proved to be acceptable and useful. Long-term consistency remains a challenge.
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CiteScore
0.60
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