K. Lipatov, A. Asatryan, G. Melkonyan, V. Kuznetsov, I. V. Gorbacheva, M.V. Yurchenko
{"title":"坏死性上肢筋膜炎的临床、诊断、治疗","authors":"K. Lipatov, A. Asatryan, G. Melkonyan, V. Kuznetsov, I. V. Gorbacheva, M.V. Yurchenko","doi":"10.18484/2305-0047.2022.1.102","DOIUrl":null,"url":null,"abstract":"Objective. To study the treatment results of patients with necrotizing fasciitis (NF) of the upper limb. Methods. The authors’ observations of 9 patients with a rare and severe disease: necrotizing fasciitis (NF) of the upper limb have been analyzed. Minor skin lesions in the area of the hand became the entry gate for any infection. The median time prior hospitalization was 4,8±1,8 (M±σ) days. Immediately upon admission, the diagnosis of upper limb NF was established in 5 patients. This was followed by emergency radical surgery. The rest were also urgently operated on, but with a diagnosis of phlegmon of the hand and in insufficient volume. They were diagnosed with NF within the first day and a second operation was performed. In most cases the lesion included tissues of the hand, forearm, and arm. Primary surgery was supplemented by staged necrectomies, the number of which averaged 4,7±1,9 per patient. The complex of intensive treatment included broad-spectrum antibiotics, anticoagulants (enoxaparin 8,000 anti-Xa IU / day). Surgical closure of postnecrectomic wounds was performed using skin plastic operations: plastics with local tissues, autodermoplasty with a split graft. Results. Most of the cases were classified as type II NF (Streptococcus pyogenes or Staphylococcus aureus). In one case, a very rare and extremely severe, NF caused by Pasteurella multocida was observed. No antibiotic-resistant strains were found. Emergency radical operation became the cornerstone of success. The need for staged necrectomy was determined by the formation of secondary necrosis in connection with severe microcirculation disorders. Extensive postnecrectomic wounds were closed after the inflammation subsided with the help of skin plastic operations. The average duration of inpatient treatment was 20,8±6,2 days. There were no lethal outcomes. Conclusion. A complex approach to the treatment of necrotising fasciitis of upper limb allowed getting positive treatment results in all cases.","PeriodicalId":38373,"journal":{"name":"Novosti Khirurgii","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"NECROTISING FASCIITIS OF UPPER LIMB: CLINIC, DIAGNOSIS, TREATMENT\",\"authors\":\"K. Lipatov, A. Asatryan, G. Melkonyan, V. Kuznetsov, I. V. Gorbacheva, M.V. Yurchenko\",\"doi\":\"10.18484/2305-0047.2022.1.102\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective. To study the treatment results of patients with necrotizing fasciitis (NF) of the upper limb. Methods. The authors’ observations of 9 patients with a rare and severe disease: necrotizing fasciitis (NF) of the upper limb have been analyzed. Minor skin lesions in the area of the hand became the entry gate for any infection. The median time prior hospitalization was 4,8±1,8 (M±σ) days. Immediately upon admission, the diagnosis of upper limb NF was established in 5 patients. This was followed by emergency radical surgery. The rest were also urgently operated on, but with a diagnosis of phlegmon of the hand and in insufficient volume. They were diagnosed with NF within the first day and a second operation was performed. In most cases the lesion included tissues of the hand, forearm, and arm. Primary surgery was supplemented by staged necrectomies, the number of which averaged 4,7±1,9 per patient. The complex of intensive treatment included broad-spectrum antibiotics, anticoagulants (enoxaparin 8,000 anti-Xa IU / day). Surgical closure of postnecrectomic wounds was performed using skin plastic operations: plastics with local tissues, autodermoplasty with a split graft. Results. Most of the cases were classified as type II NF (Streptococcus pyogenes or Staphylococcus aureus). In one case, a very rare and extremely severe, NF caused by Pasteurella multocida was observed. No antibiotic-resistant strains were found. Emergency radical operation became the cornerstone of success. The need for staged necrectomy was determined by the formation of secondary necrosis in connection with severe microcirculation disorders. Extensive postnecrectomic wounds were closed after the inflammation subsided with the help of skin plastic operations. The average duration of inpatient treatment was 20,8±6,2 days. There were no lethal outcomes. Conclusion. A complex approach to the treatment of necrotising fasciitis of upper limb allowed getting positive treatment results in all cases.\",\"PeriodicalId\":38373,\"journal\":{\"name\":\"Novosti Khirurgii\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-02-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Novosti Khirurgii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18484/2305-0047.2022.1.102\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Novosti Khirurgii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18484/2305-0047.2022.1.102","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目标。探讨上肢坏死性筋膜炎(NF)的治疗效果。方法。作者对9例罕见严重疾病:上肢坏死性筋膜炎(NF)的观察结果进行了分析。手部区域的轻微皮肤病变成为任何感染的入口。入院前中位时间为4,8±1,8 (M±σ) d。5例患者入院后立即诊断为上肢NF。随后进行了紧急根治性手术。其余的人也接受了紧急手术,但诊断为手部痰多,痰量不足。他们在第一天被诊断为NF,并进行了第二次手术。在大多数病例中,病变包括手、前臂和手臂组织。初级手术辅以分期切除,平均每例4,7±1,9例。综合强化治疗包括广谱抗生素、抗凝血药物(依诺肝素8000抗xa IU /天)。切除后伤口的外科闭合采用皮肤整形手术:局部组织整形,自体真皮成形术和分裂移植物。结果。大多数病例为II型NF(化脓性链球菌或金黄色葡萄球菌)。在一例中,观察到由多杀性巴氏杆菌引起的非常罕见和极其严重的NF。未发现耐药菌株。紧急根治性手术成为成功的基石。需要分期切除坏死是由继发性坏死的形成与严重的微循环障碍。在皮肤整形手术的帮助下,大面积的切除后伤口在炎症消退后闭合。平均住院时间20.8±6.2 d。没有致命的结果。结论。一个复杂的方法来治疗上肢坏死性筋膜炎允许得到积极的治疗结果在所有情况下。
NECROTISING FASCIITIS OF UPPER LIMB: CLINIC, DIAGNOSIS, TREATMENT
Objective. To study the treatment results of patients with necrotizing fasciitis (NF) of the upper limb. Methods. The authors’ observations of 9 patients with a rare and severe disease: necrotizing fasciitis (NF) of the upper limb have been analyzed. Minor skin lesions in the area of the hand became the entry gate for any infection. The median time prior hospitalization was 4,8±1,8 (M±σ) days. Immediately upon admission, the diagnosis of upper limb NF was established in 5 patients. This was followed by emergency radical surgery. The rest were also urgently operated on, but with a diagnosis of phlegmon of the hand and in insufficient volume. They were diagnosed with NF within the first day and a second operation was performed. In most cases the lesion included tissues of the hand, forearm, and arm. Primary surgery was supplemented by staged necrectomies, the number of which averaged 4,7±1,9 per patient. The complex of intensive treatment included broad-spectrum antibiotics, anticoagulants (enoxaparin 8,000 anti-Xa IU / day). Surgical closure of postnecrectomic wounds was performed using skin plastic operations: plastics with local tissues, autodermoplasty with a split graft. Results. Most of the cases were classified as type II NF (Streptococcus pyogenes or Staphylococcus aureus). In one case, a very rare and extremely severe, NF caused by Pasteurella multocida was observed. No antibiotic-resistant strains were found. Emergency radical operation became the cornerstone of success. The need for staged necrectomy was determined by the formation of secondary necrosis in connection with severe microcirculation disorders. Extensive postnecrectomic wounds were closed after the inflammation subsided with the help of skin plastic operations. The average duration of inpatient treatment was 20,8±6,2 days. There were no lethal outcomes. Conclusion. A complex approach to the treatment of necrotising fasciitis of upper limb allowed getting positive treatment results in all cases.