低能电子束沉积Icaritin薄膜的研究

IF 0.5 Q4 CHEMISTRY, MULTIDISCIPLINARY

Eurasian Chemico-Technological Journal Pub Date : 2021-08-30 DOI:10.18321/ectj1077

Tongfei Cheng, Jinxing Cao, Xiaohong Jiang, M. Yarmolenko, A. Rogachev, A. Rogachev

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引用次数: 1

摘要

本文采用低能束电子束沉积（EBD）方法制备了icaritin薄膜。材料试验表明，电子束沉积后，icaritin的结构和组成没有变化。然后，将薄膜切片并浸入模拟体液中，可以看出薄膜在前7天内快速释放。随着浸泡时间的延长，释放速率逐渐减慢，约20天释放量超过90%。体外细胞毒性试验表明，该膜的相对细胞活力率仍为92.32±1.30%（p<0.05），表明该膜具有良好的细胞相容性。

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Study of Icaritin Films by Low-Energy Electron Beam Deposition

In this paper, icaritin film was prepared by low-energy beam electron beam deposition (EBD). The material test showed that the structure and composition of icaritin were not changed after electron beam deposition. Then, the film was sliced and immersed in simulated body fluids, it can be seen that the film was released quickly in the first 7 days. With the extension of soaking time, the release rate gradually slowed down, and the release amount exceeded 90% in about 20 days. In vitro cytotoxicity test showed that the relative cell viability rate of the film was still 92.32±1.30% (p<0.05), indicating that the film possessed excellent cytocompatibility.

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来源期刊

Eurasian Chemico-Technological Journal CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

1.10

自引率

20.00%

发文量

审稿时长

20 weeks

期刊介绍： The journal is designed for publication of experimental and theoretical investigation results in the field of chemistry and chemical technology. Among priority fields that emphasized by chemical science are as follows: advanced materials and chemical technologies, current issues of organic synthesis and chemistry of natural compounds, physical chemistry, chemical physics, electro-photo-radiative-plasma chemistry, colloids, nanotechnologies, catalysis and surface-active materials, polymers, biochemistry.