Chronic Limb-Threatening Ischemia: Current Perspective

Editorial Chronic limb-threatening ischemia (CLTI) is associated with high mortality, amputation, and impaired quality of life. As clinical syndrome defined by the presence of peripheral artery disease (PAD) in combination with ischemic rest pain, gangrene, or a lower limb ulceration more than 2 weeks of duration [1]. CLTI represents the end stage of peripheral artery disease (PAD), a problem of growing prevalence and increased health care costs around [2]. CLTI is a highly morbid disease, incurring significant mortality, limb loss, pain, and diminished health-related quality of life (HRQL) among those afflicted. Multiple health care specialists are involved in the management of CLTI, yet lack of public awareness and the frequent