Paolo Piersanti, Kristen L. White, B. Dragnea, R. Temam
{"title":"在静态和时间依赖情况下,用于近似病毒衣壳在平面上的变形的三维离散模型","authors":"Paolo Piersanti, Kristen L. White, B. Dragnea, R. Temam","doi":"10.1142/s0219530522400024","DOIUrl":null,"url":null,"abstract":". In this paper we present a three-dimensional discrete model governing the deformation of a viral capsid, modelled as a regular icosahedron and subjected not to cross a given flat rigid surface on which it initially lies in correspondence of one vertex only. First, we set up the model in the form of a set of variational inequalities posed over a non-empty, closed and convex subset of a suitable space. Secondly, we show the existence and uniqueness of the solution for the proposed model. Thirdly, we numerically test this model and we observe that the outputs of the numerical experiments comply with physics. Finally, we establish the existence of solutions for the corresponding time-dependent obstacle problem.","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2022-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"A three-dimensional discrete model for approximating the deformation of a viral capsid subjected to lying over a flat surface in the static and time-dependent case\",\"authors\":\"Paolo Piersanti, Kristen L. White, B. Dragnea, R. Temam\",\"doi\":\"10.1142/s0219530522400024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\". In this paper we present a three-dimensional discrete model governing the deformation of a viral capsid, modelled as a regular icosahedron and subjected not to cross a given flat rigid surface on which it initially lies in correspondence of one vertex only. First, we set up the model in the form of a set of variational inequalities posed over a non-empty, closed and convex subset of a suitable space. Secondly, we show the existence and uniqueness of the solution for the proposed model. Thirdly, we numerically test this model and we observe that the outputs of the numerical experiments comply with physics. Finally, we establish the existence of solutions for the corresponding time-dependent obstacle problem.\",\"PeriodicalId\":2,\"journal\":{\"name\":\"ACS Applied Bio Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2022-08-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Bio Materials\",\"FirstCategoryId\":\"100\",\"ListUrlMain\":\"https://doi.org/10.1142/s0219530522400024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1142/s0219530522400024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
A three-dimensional discrete model for approximating the deformation of a viral capsid subjected to lying over a flat surface in the static and time-dependent case
. In this paper we present a three-dimensional discrete model governing the deformation of a viral capsid, modelled as a regular icosahedron and subjected not to cross a given flat rigid surface on which it initially lies in correspondence of one vertex only. First, we set up the model in the form of a set of variational inequalities posed over a non-empty, closed and convex subset of a suitable space. Secondly, we show the existence and uniqueness of the solution for the proposed model. Thirdly, we numerically test this model and we observe that the outputs of the numerical experiments comply with physics. Finally, we establish the existence of solutions for the corresponding time-dependent obstacle problem.