低精浆抗氧化电位对精液质量和男性生育能力的影响

Passer Journal Pub Date : 2019-03-01 DOI:10.24271/psr.02
A. Palani, Nora Sabah Asdallh
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引用次数: 2

摘要

确定影响正常精子功能的因素是非常重要的。分析精浆中新的生化参数,以确定影响正常精子功能的生化因素。研究小组包括不孕不育组(n=31)和正常精子症组(n=27),并以健康男性为对照(n=24)。根据世界卫生组织(2010年)对患者进行了选择和检查。除精液分析外,还分析了各样本精浆中的生化参数,包括;总抗氧化能力,过氧化氢酶,谷胱甘肽还原酶,谷胱甘肽和丙二醛。结果表明:与对照组相比,弱精子症和正精子症不育组的精浆总抗氧化能力降低,过氧化氢酶水平显著降低,丙二醛水平显著升高,弱精子症组的谷胱甘肽水平显著降低。抗氧化剂在精子保护中起着重要的作用,它通过扰乱活性氧生成的平衡,破坏精子质膜,导致精子活性降低,使卵子受精的能力下降。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Low Seminal Plasma Antioxidant Potential on Semen Quality and Male Fertility
It is very important to identify the factors which affect normal sperm functions. New Bio-chemical parameters in seminal plasma were analyzed to determine the biochemical factors that affect normal sperm function. The research groups consists of infertile groups Asthenozoospermia (n=31) and Normozoospermia (n=27) with a healthy men as a control (n=24). The patients have been selected and examined according to the World Health Organization (2010). In addition the seminal fluid analysis the biochemical parameters were analyzed in the seminal plasma of each sample including; Total antioxidant capacity, Catalase, Glutathione Reductase , glutathione and Malondialdehyde.Results showed a decrease in seminal plasma total antioxidant capacity of Astheno-zoospermia and Normozoospermia , and a significance decrease in catalase level for both infertile groups, Malondialdehyde level significantly increased in both infertile groups and Glutathione level significantly decreased in Asthenozoospermia group as compared to control group. Antioxidants have an important role in sperm protection via disturbing the balance in ROS production which destroys sperm plasma membrane causing loss sperm activity and it's ability to fertilize the egg.
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来源期刊
CiteScore
0.50
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0.00%
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23
审稿时长
12 weeks
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