M. Shirley, Joilane Alves Pereira-Freire, Karoline de Macêdo Gonçalves Frota, Jesuana Oliveira Lemos, J. Wells, Lays Arnaud Rosal Lopes Rodrigues, Larisse Monteles Nascimento, Valdenir Queiroz Ribeiro, Patrícia Helen de Carvalho Rondó
{"title":"评估颈围作为5-8岁巴西儿童心脏代谢风险升高结果的预测指标","authors":"M. Shirley, Joilane Alves Pereira-Freire, Karoline de Macêdo Gonçalves Frota, Jesuana Oliveira Lemos, J. Wells, Lays Arnaud Rosal Lopes Rodrigues, Larisse Monteles Nascimento, Valdenir Queiroz Ribeiro, Patrícia Helen de Carvalho Rondó","doi":"10.1080/2574254x.2020.1738837","DOIUrl":null,"url":null,"abstract":"ABSTRACT Background: Childhood overweight and obesity is a global health problem that continues to worsen in many low- and middle-income countries. Low-cost measurements for monitoring overweight and relative metabolic risk, such as neck circumference (NC), should be evaluated in different populations and age groups. Aim: To test associations of NC and BMI with cardiometabolic parameters in 5-8-year-old Brazilian children. Methods: This cross-sectional study carried out from 2004–2006 measured height, weight and NC by anthropometry, and estimated fat and fat-free mass by bioelectrical impedance. Cardiometabolic risk factors assessed were systolic and diastolic blood pressure, high- and low-density lipoprotein cholesterol, triglycerides, and homeostatic model assessment of insulin resistance (HOMA). Associations of NC and BMI with cardiometabolic risk factors were tested using multiple regression and precision-recall plot analysis. Results: Analyses included 371 children (52% female). NC associated positively with BMI, fat mass, and fat-free mass, and with systolic blood pressure and HOMA following adjustment for age in sex-stratified multiple regression models. However, the latter relationships largely disappeared following adjustment for BMI. Area under the curve for NC or BMI in association with systolic blood pressure or HOMA >90th percentile was low in the pooled sample, indicating poor classifier performance. Conclusions: NC and BMI demonstrated similar associations with cardiometabolic risk factors, although NC mostly did not correlate with risk factors independently of BMI. In contrast to previous studies, NC was a poor classifier of cardiometabolic risk factors in children. The association of NC with both fat and fat-free mass may aid in explaining its poor performance.","PeriodicalId":72570,"journal":{"name":"Child and adolescent obesity (Abingdon, England)","volume":"3 1","pages":"1 - 19"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/2574254x.2020.1738837","citationCount":"2","resultStr":"{\"title\":\"Evaluation of neck circumference as a predictor of elevated cardiometabolic risk outcomes in 5–8-year-old Brazilian children\",\"authors\":\"M. Shirley, Joilane Alves Pereira-Freire, Karoline de Macêdo Gonçalves Frota, Jesuana Oliveira Lemos, J. Wells, Lays Arnaud Rosal Lopes Rodrigues, Larisse Monteles Nascimento, Valdenir Queiroz Ribeiro, Patrícia Helen de Carvalho Rondó\",\"doi\":\"10.1080/2574254x.2020.1738837\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABSTRACT Background: Childhood overweight and obesity is a global health problem that continues to worsen in many low- and middle-income countries. Low-cost measurements for monitoring overweight and relative metabolic risk, such as neck circumference (NC), should be evaluated in different populations and age groups. Aim: To test associations of NC and BMI with cardiometabolic parameters in 5-8-year-old Brazilian children. Methods: This cross-sectional study carried out from 2004–2006 measured height, weight and NC by anthropometry, and estimated fat and fat-free mass by bioelectrical impedance. Cardiometabolic risk factors assessed were systolic and diastolic blood pressure, high- and low-density lipoprotein cholesterol, triglycerides, and homeostatic model assessment of insulin resistance (HOMA). Associations of NC and BMI with cardiometabolic risk factors were tested using multiple regression and precision-recall plot analysis. Results: Analyses included 371 children (52% female). NC associated positively with BMI, fat mass, and fat-free mass, and with systolic blood pressure and HOMA following adjustment for age in sex-stratified multiple regression models. However, the latter relationships largely disappeared following adjustment for BMI. Area under the curve for NC or BMI in association with systolic blood pressure or HOMA >90th percentile was low in the pooled sample, indicating poor classifier performance. Conclusions: NC and BMI demonstrated similar associations with cardiometabolic risk factors, although NC mostly did not correlate with risk factors independently of BMI. In contrast to previous studies, NC was a poor classifier of cardiometabolic risk factors in children. The association of NC with both fat and fat-free mass may aid in explaining its poor performance.\",\"PeriodicalId\":72570,\"journal\":{\"name\":\"Child and adolescent obesity (Abingdon, England)\",\"volume\":\"3 1\",\"pages\":\"1 - 19\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/2574254x.2020.1738837\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Child and adolescent obesity (Abingdon, England)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/2574254x.2020.1738837\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Child and adolescent obesity (Abingdon, England)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/2574254x.2020.1738837","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evaluation of neck circumference as a predictor of elevated cardiometabolic risk outcomes in 5–8-year-old Brazilian children
ABSTRACT Background: Childhood overweight and obesity is a global health problem that continues to worsen in many low- and middle-income countries. Low-cost measurements for monitoring overweight and relative metabolic risk, such as neck circumference (NC), should be evaluated in different populations and age groups. Aim: To test associations of NC and BMI with cardiometabolic parameters in 5-8-year-old Brazilian children. Methods: This cross-sectional study carried out from 2004–2006 measured height, weight and NC by anthropometry, and estimated fat and fat-free mass by bioelectrical impedance. Cardiometabolic risk factors assessed were systolic and diastolic blood pressure, high- and low-density lipoprotein cholesterol, triglycerides, and homeostatic model assessment of insulin resistance (HOMA). Associations of NC and BMI with cardiometabolic risk factors were tested using multiple regression and precision-recall plot analysis. Results: Analyses included 371 children (52% female). NC associated positively with BMI, fat mass, and fat-free mass, and with systolic blood pressure and HOMA following adjustment for age in sex-stratified multiple regression models. However, the latter relationships largely disappeared following adjustment for BMI. Area under the curve for NC or BMI in association with systolic blood pressure or HOMA >90th percentile was low in the pooled sample, indicating poor classifier performance. Conclusions: NC and BMI demonstrated similar associations with cardiometabolic risk factors, although NC mostly did not correlate with risk factors independently of BMI. In contrast to previous studies, NC was a poor classifier of cardiometabolic risk factors in children. The association of NC with both fat and fat-free mass may aid in explaining its poor performance.