脉冲电磁场抑制间充质干细胞脂肪形成的细胞机制研究进展

Q3 Agricultural and Biological Sciences

OnLine Journal of Biological Sciences Pub Date : 2023-02-01 DOI:10.3844/ojbsci.2023.177.186

P. Sari, N. F. Mazfufah, Umiatin, D. Suryandari, S. W. Lestari, L. Yunaini

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引用次数: 0

摘要

: PEMF是一种利用电流的方法，利用一个由动态电流供电的线圈，它会在线圈中产生动态磁场。在过去的几十年里，人们知道PEMF有可能被用作治疗肥胖的一种方式。因此，人们在体外研究了pemf对间充质干细胞(MSC)脂肪生成的抑制作用。但是，使用PEMF疗法抑制脂肪生成仍有许多挑战。对暴露于PEMF的细胞中发生的机制的了解仍然非常少。本文综述了PEMF体外抑制脂肪生成的研究进展及其机制。在未来，希望本综述可以为利用PEMF抑制脂肪生成的体内研究和临床试验提供基础参考

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Review of Cellular Mechanism of Pulsed Electromagnetic Field (PEMF) in Inhibiting Adipogenesis of Mesenchymal Stem Cells

: PEMF is a method that utilizes electric current using a coil that is powered by dynamic electric current, it will cause a dynamic magnetic field in the coil. In the last few decades, it is known that PEMF has the potential to be used as a modality in the treatment of obesity. For this reason, PEMFs have been studied in vitro as their effect in inhibiting the adipogenesis of Mesenchymal Stem Cells (MSC). But the use of PEMF therapy in inhibiting adipogenesis still has many challenges. Understanding of the mechanisms that occur in cells that are exposed to PEMF is also still very slight. This article reviews the studies that investigated in vitro effect of PEMF in inhibiting adipogenesis studies and the underlying mechanism. In the future, it is hoped that this review can be used as a basic reference for in vivo research and clinical trials related to inhibiting adipogenesis using PEMF

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来源期刊

OnLine Journal of Biological Sciences Agricultural and Biological Sciences-Agricultural and Biological Sciences (all)

CiteScore

2.10

自引率

0.00%

发文量

期刊介绍： :: Cell biology :: Developmental biology :: Structural biology :: Microbiology :: Molecular biology & genetics :: Biochemistry :: Biotechnology :: Biodiversity :: Ecology :: Marine biology :: Plant biology :: Bioinformatics