Incidence of breast cancer among blood groups of women in the holy Governorate of Karbala

Introduction: Breast cancer is a significant problem that affects women all over the world and is a leading cause of death among these patients. ABO blood groups are stable and vary by socioeconomic, geographical, and ethnic groupings. Blood type affects susceptibility and results. Objective: Previous studies have discovered a correlation between ABO blood type and Rh system as risk factors for breast cancer. Aim: To identify the association of breast cancer prevalence between women’s blood groups and the Rh factor system in Karbala Governorate. Materials and Methods: A total of 1026 women were chosen, with 736 cases and 290 controls. The case group includes patients with breast cancer, and all of them had their cancer diagnosis confirmed by biopsy. The control group consisted of women who had never been diagnosed with cancer of breast. Results: Blood group type O (39.7%), blood group type A (26.1%), blood group type B (25.4%), and blood group type AB (8.8%) were the most common ABO blood types among cancer of breast patients. The percentages of groups of ABO blood for healthy donor control were as follows: blood group type O (40.0%), blood group type A (27.6%), blood group type B (21.7%), and AB (10.7%) with P = 0.05 or higher. There is a significant difference in the Rh factor between breast cancer patients and healthy control (P = 0.003). There were noticeable differences in age categories between patients diagnosed with breast cancer and the controls in this study (P = 0.000). Conclusion: There is no correlation between ABO blood types and breast cancer in this group of Iraqi women. There is a statistically significant difference, with a P value of 0.003, between patients diagnosed with breast cancer and healthy controls in terms of the Rh factor.