Ling Zhao, Li-Hai Tan, Guoliang Cheng, Yu Miao, Xiang-ming Zhou, Shigang Du, Jia Wang, Yang Yang, Ke Tingyu
{"title":"基于银+消毒液取样针的米格列醇治疗糖尿病的效果分析","authors":"Ling Zhao, Li-Hai Tan, Guoliang Cheng, Yu Miao, Xiang-ming Zhou, Shigang Du, Jia Wang, Yang Yang, Ke Tingyu","doi":"10.1166/nnl.2020.3132","DOIUrl":null,"url":null,"abstract":"The present work selected 120 patients, affected by diabetes, as control subjects in the Affiliated Hospital of Kunming Medical University. According to the principle of random distribution, two groups were established, miglitol study group (65 cases) and metformin control group (55\n cases). The Ag + disinfectant sampling needle is a rapid detection tool to evaluate the efficacy of diabetes in both groups. The related biochemical indexes of the patients were measured before and after treatment at the 3rd, 6th, and 12th weeks. The test results showed that there were significant\n differences in fasting blood glucose value (FBG) and postprandial blood glucose value (2hFBG) among the two groups after 3-, 6-, and 12-month treatment. With the extension of treatment, the blood glucose level of diabetic patients gradually stabilized. Fasting insulin level (FINS) and postprandial\n two-hour insulin level (2hINS) increased gradually. At the 12th week, by measuring the HbA1c level of the patients, it was found decreasing significantly. In detail, the study group decreased more significantly than the control group, and the incidence of adverse reactions during treatment\n was 10.8% and 23.6%, respectively, with a significant statistical significance (P < 0 05). Meanwhile, we measured other biochemical indexes of patients from both groups after drug treatment. At the 6th week, the levels of glycosylated glycoprotein (HbA1c), triglyceride (TG), high-density\n lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) in the study group decreased more than in the control group. Therefore, miglitol shows a better hypoglycemic effect on type 2 diabetes, and the gastrointestinal adverse reactions are lesser than metformin, which\n is more worthy in clinical application.","PeriodicalId":18871,"journal":{"name":"Nanoscience and Nanotechnology Letters","volume":"12 1","pages":"550-555"},"PeriodicalIF":0.0000,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis of the Effect of Miglitol in the Treatment of Diabetes Mellitus Based on Ag+ Disinfectant Sampling Needle\",\"authors\":\"Ling Zhao, Li-Hai Tan, Guoliang Cheng, Yu Miao, Xiang-ming Zhou, Shigang Du, Jia Wang, Yang Yang, Ke Tingyu\",\"doi\":\"10.1166/nnl.2020.3132\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The present work selected 120 patients, affected by diabetes, as control subjects in the Affiliated Hospital of Kunming Medical University. According to the principle of random distribution, two groups were established, miglitol study group (65 cases) and metformin control group (55\\n cases). The Ag + disinfectant sampling needle is a rapid detection tool to evaluate the efficacy of diabetes in both groups. The related biochemical indexes of the patients were measured before and after treatment at the 3rd, 6th, and 12th weeks. The test results showed that there were significant\\n differences in fasting blood glucose value (FBG) and postprandial blood glucose value (2hFBG) among the two groups after 3-, 6-, and 12-month treatment. With the extension of treatment, the blood glucose level of diabetic patients gradually stabilized. Fasting insulin level (FINS) and postprandial\\n two-hour insulin level (2hINS) increased gradually. At the 12th week, by measuring the HbA1c level of the patients, it was found decreasing significantly. In detail, the study group decreased more significantly than the control group, and the incidence of adverse reactions during treatment\\n was 10.8% and 23.6%, respectively, with a significant statistical significance (P < 0 05). Meanwhile, we measured other biochemical indexes of patients from both groups after drug treatment. At the 6th week, the levels of glycosylated glycoprotein (HbA1c), triglyceride (TG), high-density\\n lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) in the study group decreased more than in the control group. Therefore, miglitol shows a better hypoglycemic effect on type 2 diabetes, and the gastrointestinal adverse reactions are lesser than metformin, which\\n is more worthy in clinical application.\",\"PeriodicalId\":18871,\"journal\":{\"name\":\"Nanoscience and Nanotechnology Letters\",\"volume\":\"12 1\",\"pages\":\"550-555\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nanoscience and Nanotechnology Letters\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1166/nnl.2020.3132\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanoscience and Nanotechnology Letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1166/nnl.2020.3132","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Analysis of the Effect of Miglitol in the Treatment of Diabetes Mellitus Based on Ag+ Disinfectant Sampling Needle
The present work selected 120 patients, affected by diabetes, as control subjects in the Affiliated Hospital of Kunming Medical University. According to the principle of random distribution, two groups were established, miglitol study group (65 cases) and metformin control group (55
cases). The Ag + disinfectant sampling needle is a rapid detection tool to evaluate the efficacy of diabetes in both groups. The related biochemical indexes of the patients were measured before and after treatment at the 3rd, 6th, and 12th weeks. The test results showed that there were significant
differences in fasting blood glucose value (FBG) and postprandial blood glucose value (2hFBG) among the two groups after 3-, 6-, and 12-month treatment. With the extension of treatment, the blood glucose level of diabetic patients gradually stabilized. Fasting insulin level (FINS) and postprandial
two-hour insulin level (2hINS) increased gradually. At the 12th week, by measuring the HbA1c level of the patients, it was found decreasing significantly. In detail, the study group decreased more significantly than the control group, and the incidence of adverse reactions during treatment
was 10.8% and 23.6%, respectively, with a significant statistical significance (P < 0 05). Meanwhile, we measured other biochemical indexes of patients from both groups after drug treatment. At the 6th week, the levels of glycosylated glycoprotein (HbA1c), triglyceride (TG), high-density
lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) in the study group decreased more than in the control group. Therefore, miglitol shows a better hypoglycemic effect on type 2 diabetes, and the gastrointestinal adverse reactions are lesser than metformin, which
is more worthy in clinical application.