基于银+消毒液取样针的米格列醇治疗糖尿病的效果分析

Ling Zhao, Li-Hai Tan, Guoliang Cheng, Yu Miao, Xiang-ming Zhou, Shigang Du, Jia Wang, Yang Yang, Ke Tingyu
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引用次数: 0

摘要

本研究选取昆明医科大学附属医院120例糖尿病患者作为对照。根据随机分布原则,设米格利托研究组(65例)和二甲双胍对照组(55例)两组。Ag+消毒剂采样针是评估两组糖尿病疗效的快速检测工具。分别于治疗前、治疗后第3、6、12周测定患者的相关生化指标。试验结果显示,治疗3个月、6个月和12个月后,两组的空腹血糖值(FBG)和餐后血糖值(2hFBG)存在显著差异。随着治疗的延长,糖尿病患者的血糖水平逐渐稳定。空腹胰岛素水平(FINS)和餐后2小时胰岛素水平(2INS)逐渐升高。在第12周,通过测量患者的HbA1c水平,发现其显著降低。具体而言,研究组比对照组下降更为显著,治疗期间不良反应发生率分别为10.8%和23.6%,具有显著统计学意义(P<0.05)。同时测定两组患者药物治疗后的其他生化指标。第6周,研究组的糖化糖蛋白(HbA1c)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆甾醇(LDL-C)水平比对照组下降更多。因此,米格利托对2型糖尿病显示出更好的降血糖作用,胃肠道不良反应比二甲双胍少,更值得临床应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of the Effect of Miglitol in the Treatment of Diabetes Mellitus Based on Ag+ Disinfectant Sampling Needle
The present work selected 120 patients, affected by diabetes, as control subjects in the Affiliated Hospital of Kunming Medical University. According to the principle of random distribution, two groups were established, miglitol study group (65 cases) and metformin control group (55 cases). The Ag + disinfectant sampling needle is a rapid detection tool to evaluate the efficacy of diabetes in both groups. The related biochemical indexes of the patients were measured before and after treatment at the 3rd, 6th, and 12th weeks. The test results showed that there were significant differences in fasting blood glucose value (FBG) and postprandial blood glucose value (2hFBG) among the two groups after 3-, 6-, and 12-month treatment. With the extension of treatment, the blood glucose level of diabetic patients gradually stabilized. Fasting insulin level (FINS) and postprandial two-hour insulin level (2hINS) increased gradually. At the 12th week, by measuring the HbA1c level of the patients, it was found decreasing significantly. In detail, the study group decreased more significantly than the control group, and the incidence of adverse reactions during treatment was 10.8% and 23.6%, respectively, with a significant statistical significance (P < 0 05). Meanwhile, we measured other biochemical indexes of patients from both groups after drug treatment. At the 6th week, the levels of glycosylated glycoprotein (HbA1c), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) in the study group decreased more than in the control group. Therefore, miglitol shows a better hypoglycemic effect on type 2 diabetes, and the gastrointestinal adverse reactions are lesser than metformin, which is more worthy in clinical application.
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来源期刊
Nanoscience and Nanotechnology Letters
Nanoscience and Nanotechnology Letters Physical, Chemical & Earth Sciences-MATERIALS SCIENCE, MULTIDISCIPLINARY
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2.6 months
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