Zodia Leaves（Evodia Suaveolens Scheff）油作为埃及伊蚊驱蚊剂在巴布亚的效果

Q3 Pharmacology, Toxicology and Pharmaceutics

Jordan Journal of Pharmaceutical Sciences Pub Date : 2023-06-25 DOI:10.35516/jjps.v16i2.1321

Y. R. Yabansabra, Sally Felter Bebari, E. Simaremare

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引用次数: 0

摘要

登革出血热是由感染登革热病毒引起的一种疾病。它是通过使用驱蚊剂来控制的，这种驱蚊剂可以保护人类免受蚊子叮咬。该社区使用的驱蚊剂之一包括避蚊胺化学物质，但也需要用于对付蚊子的天然驱蚊剂，如zodia植物。叶（Evodia suaveolens Scheff）含有芳樟醇和松烯化合物，以及吴茱萸二胺和芸香碱。芳樟醇的作用是破坏蚊子的神经系统，从而引起惊厥和死亡。因此，本研究旨在配制和评价zodia油，并用驱蚊力法测试其作为驱蚊剂（埃及伊蚊L）的有效性。制备的制剂具有25%、50%和75%的不同浓度。基于结果，式I（25%）对0、1、2和3小时的保护能力分别为100%、100%、89.28%和92.85%。此外，配方II（50%浓度）的保护力分别为100%、100%、90.90%和91.66%，而第三配方（75%浓度）的防护力分别为10%、100%、96.15%和93.33%。

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The Effectiveness of Zodia Leaves (Evodia Suaveolens Scheff) Oil as Aedes aegypti L Mosquito Repellent in Papua

Dengue hemorrhagic fever (DHF) is a disease caused by infection with the dengue virus. It is controlled by using repellents that protect humans from mosquito bites. One of the repellents used by the community includes DEET chemicals but natural repellents used against mosquitoes such as the zodia plant are also needed. Zodia leaves (Evodia suaveolens Scheff) contain linalool and -pinene compounds as well as evodiamine and rutacarpine. Linalool functions by disrupting the nervous system in mosquitoes thereby causing convulsion and death. Therefore, this study aims to formulate and evaluate the zodia oil and test its effectiveness as a mosquito repellent (Aedes aegypti L) with repelling power method. The formulations were prepared with various concentrations of 25 %, 50 %, and 75 %. Based on the results, the protective power of Formula I (25 %) for 0, 1st, 2nd, and 3rd hours, respectively, was 100%, 100 %, 89.28 %, and 92.85 %. Furthermore, Formula II (50 % concentration) showed a protective power of 100 %, 100 %, 90.90 % and 91.66 %, while the third Formula (75 % concentration) showed a protection power of 100 %, 100 %, 96.15% and 93.33%. Therefore, it was concluded that the three zodia oil formulas are effective as a repellent against Aedes aegypti L mosquitoes.

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来源期刊

Jordan Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

1.70

自引率

0.00%

发文量

期刊介绍： The Jordan Journal of Pharmaceutical Sciences (JJPS) is a scientific, bi-annual, peer-reviewed publication that will focus on current topics of interest to the pharmaceutical community at large. Although the JJPS is intended to be of interest to pharmaceutical scientists, other healthy workers, and manufacturing processors will also find it most interesting and informative. Papers will cover basic pharmaceutical and applied research, scientific commentaries, as well as views, reviews. Topics on products will include manufacturing process, quality control, pharmaceutical engineering, pharmaceutical technology, and philosophies on all aspects of pharmaceutical sciences. The editorial advisory board would like to place an emphasis on new and innovative methods, technologies, and techniques for the pharmaceutical industry. The reader will find a broad range of important topics in this first issue.