早期子宫内膜癌或子宫内膜不典型增生患者保留生育能力的生殖进展

Q4 Medicine

Gynecology and Obstetrics Clinical Medicine Pub Date : 2022-12-01 DOI:10.1016/j.gocm.2022.10.005

Jiao Yu, Yangyang Zhang, Huixia Yang, Yang Xu

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引用次数: 0

摘要

子宫内膜癌(EC)是全球第四大常见女性癌症，其发病率每年都在上升。10%-15%的年轻患者被诊断为EC。育龄期早期子宫内膜癌或不典型增生的患者，分娩后应考虑手术切除子宫。对于生殖医生和肿瘤学家来说，帮助这些患者尽快安全怀孕是一个巨大的挑战。本文将对保守治疗的最新进展、保留生育能力的候选药物、分子检测的应用、生育结果和后续治疗进行综述，旨在激发人们更多的思考。

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Reproductive advance of fertility preservation in patients with early endometrial carcinoma or endometrial atypical hyperplasia

Endometrial cancer (EC) is the fourth common cancer in women worldwide with its incidence rising each year. 10%–15% young patients are diagnosed of EC. For patients of childbearing age with early endometrial cancer or atypical hyperplasia, it is necessary to consider surgical removal of uterus after they have given birth. It is a big challenge for reproductive doctors and oncologists to help such patients get pregnant safely as soon as possible. In this article, we will review the latest progress in conservative treatment and candidates for fertility preservation, application of molecular detection, the fertility outcome and follow-up treatment which aims to stimulate more thinking.

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来源期刊

Gynecology and Obstetrics Clinical Medicine Medicine-Obstetrics and Gynecology

CiteScore

0.70

自引率

0.00%

发文量

审稿时长

18 weeks