A strong system of magnetic nanocatalysts in absorbing and releasing ampicillin along with its antibacterial properties

Background: Magnetic nanoparticles are the main source of synthesis and design of magnetic nanocatalysts, which are obtained from iron salts by chemical co-precipitation method. Objective: The main goal of this research is to investigate the absorption, release and antibacterial properties of magnetic nanocatalysts with silica coating and silica/amine linker. Methods: The structure of the obtained nanocatalyst is detected by several analyzes such as SEM, TEM, EDX and IR. Results: Here is reaction between the ampicillin 10 µl (25 µg/ml) and the Fe3O4@SiO2 and Fe3O4@SiO2/NH magnetic nanocatalyst 200 mg (2 mole%), under 25°C and double distilled water. In this way, the amount of absorbed ampicillin on MNPs@silica/amine structure in covalent is more than MNPs@silica structure in non-covalent bonding, i.e. 85 to 65%, but the rate of release in non-covalent is above 90%, but in covalent is less than 80%. Also, the bactericidal properties of nanocatalysts have been tested separately at a temperature of 37 degrees for the non-covalent type are more than 80% compared to Covalance form is 70%. Conclusions: The overall result was that the percentage efficiency of the absorption/release reaction in the non-covalent bonding state was much better and about 10% more release.