鱼腥草精油通过纠正IP3R介导的Ca2+中断缓解哮喘气道重塑

IF 4.4 2区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

The FASEB Journal Pub Date : 2021-05-01 DOI:10.1096/FASEBJ.2021.35.S1.05303

Alexis Shiying Huang, Chun-hin Hung, B. Tong, Aston Jiaxi Wu, Jingxuan Bai, Xiuqiong Fu, Zhiling Yu, K. Cheung

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引用次数: 2

摘要

哮喘是一种常见的慢性气道炎症性疾病，在发作期间会导致气道狭窄。β-肾上腺素能激动剂在哮喘发作期间提供暂时的气道放松。长期使用皮质类固醇可以改善哮喘，但可能会给患者带来不良反应。因此，迫切需要一种替代或补充的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Houttuynia Cordata Essential Oil Mitigates Airway Remodeling in Asthma by Rectifying IP3R‐mediated Ca2+ Disruption

Asthma is a common chronic airway inflammatory disease that leads to airway narrowing during the attacks. Beta‐adrenergic agonists provide temporary relaxation of airway during asthma attacks. While long‐term usage of corticosteroids could improve asthma but it may bring adverse effects to the patients. Thus, an alternative or supplementary therapeutic approach is urgently needed.

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来源期刊

The FASEB Journal 生物-生化与分子生物学

CiteScore

9.20

自引率

2.10%

发文量

6243

审稿时长

3 months

期刊介绍： The FASEB Journal publishes international, transdisciplinary research covering all fields of biology at every level of organization: atomic, molecular, cell, tissue, organ, organismic and population. While the journal strives to include research that cuts across the biological sciences, it also considers submissions that lie within one field, but may have implications for other fields as well. The journal seeks to publish basic and translational research, but also welcomes reports of pre-clinical and early clinical research. In addition to research, review, and hypothesis submissions, The FASEB Journal also seeks perspectives, commentaries, book reviews, and similar content related to the life sciences in its Up Front section.