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引用次数: 0
摘要
Roger Pertwee在BNA 2019神经科学节(4月14日至17日,爱尔兰都柏林)上与助理编辑Jennifer Straiton进行了交谈,他在会上发表了题为“某些植物和合成大麻素的药理作用和潜在的新治疗用途”的演讲。Roger Pertwee是阿伯丁大学(英国苏格兰)的名誉教授,自1974年以来一直活跃于该校的科学研究。他在英国牛津大学开始了他的研究生涯,在那里他获得了三个研究生学位:生物化学硕士、药理学博士和生理科学博士。他的研究重点是大麻素的药理学,包括其作用机制和潜在的治疗用途。他在该领域的多项重大发现中发挥了重要作用,包括:;大麻素CB1受体变构位点的发现,各种植物大麻素的药理学特征,以及内源性大麻素和新型合成大麻素共同发现和表征。
Pharmacology and potential therapeutic uses of some cannabinoids
Roger Pertwee speaks to Jennifer Straiton, Assistant Editor, at the BNA 2019 Festival of Neuroscience (14–17 April, Dublin, Ireland), where he gave a talk titled ‘Pharmacological actions and potential novel therapeutic uses of certain plant and synthetic cannabinoids’. Roger Pertwee is an Emeritus Professor at the University of Aberdeen (Scotland, UK), where he has been active in scientific research since 1974. He began his research career at the University of Oxford (UK) where he gained three postgraduate degrees: an MA in biochemistry, a DPhil in pharmacology and a DSc in physiological sciences. His research focuses on the pharmacology of cannabinoids, both on their mechanisms of action and on their potential therapeutic uses. He has held major roles in multiple major discoveries in the field including; the discovery of a cannabinoid CB1 receptor allosteric site, the pharmacological characterization of various phytocannabinoids as well as the co-discovery of endocannabinoids and the co-discovery and characterization of novel synthetic cannabinoids.
期刊介绍:
The neurological landscape is changing rapidly. From the technological perspective, advanced molecular approaches and imaging modalities have greatly increased our understanding of neurological disease, with enhanced prospects for effective treatments in common but very serious disorders such as stroke, epilepsy, multiple sclerosis and Parkinson’s disease. Nevertheless, at the same time, the healthcare community is increasingly challenged by the rise in neurodegenerative diseases consequent upon demographic changes in developed countries.