精神分裂症谱系障碍的疼痛敏感性:近期研究的述评

IF 1.2 Q4 PSYCHIATRY
A. González-Rodríguez, J. Labad, M. Seeman
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引用次数: 7

摘要

许多精神分裂症患者似乎对身体疼痛相对免疫,而其他人则抱怨持续疼痛。这可能是由精神病患者疼痛感觉阈值的紊乱或改变引起的,这一可能性有一些初步证据。疼痛感知的不一致可能部分由患者接受的治疗来解释,但治疗幼稚的患者对疼痛的反应也存在差异。这表明疼痛敏感性降低可能代表一种特定的精神病内表型。到目前为止,很少有实验研究调查精神病患者的感觉阈值、疼痛模式或其他有助于感知或表达身体疼痛的因素。PubMed和Google Scholar对这一主题的信息进行了数字搜索。其结果是一项非系统的叙述性综述,重点关注精神病患者疼痛敏感性的最新临床和实验结果。重要的是,身体和精神疼痛是紧密相连的结构,可能很难区分。我们希望这篇综述能在精神分裂症的具体背景下为该领域提供一些清晰的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pain Sensitivity in Schizophrenia Spectrum Disorders: A Narrative Review of Recent Work
Many patients with schizophrenia seem relatively immune to physical pain while others complain of constant pain. This may result from disturbances or alterations of the sensory threshold for pain in populations with psychosis, a possibility for which there is some preliminary evidence. The inconsistency in pain perception may, in part, be explained by the treatments patients receive, but treatment-naïve patients also exhibit differences in response to pain. This suggests that decreased pain sensitivity may represent a specific psychosis endophenotype. Thus far, few experimental studies have investigated sensory thresholds, pain modalities, or other factors contributing to the perception or expression of physical pain in psychosis. A digital search for information on this topic was conducted in PubMed and Google Scholar. The result is a non-systematic, narrative review focusing on recent clinical and experimental findings of pain sensitivity in patients with psychosis. Importantly, physical and mental pain are closely connected constructs that may be difficult to differentiate. Our hope is that the review provides some clarity to the field in the specific context of schizophrenia.
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来源期刊
CiteScore
1.90
自引率
0.00%
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审稿时长
11 weeks
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