Ippei Miyamoto, Tetsuo Shimizu, Shunji Yokota, Yuji Yamakawa, Haruyasu Sakuranaka, K. Igei, N. Okamoto, Y. Gon
{"title":"HIV感染晚期肺癌治疗耐药1例","authors":"Ippei Miyamoto, Tetsuo Shimizu, Shunji Yokota, Yuji Yamakawa, Haruyasu Sakuranaka, K. Igei, N. Okamoto, Y. Gon","doi":"10.2482/haigan.62.1033","DOIUrl":null,"url":null,"abstract":"━━ Background. Antiretroviral therapy has been introduced to improve the prognosis of patients with human immunodeficiency virus (HIV) infection, and as a result, non-AIDS-defining cancer (NADC) may af-fect the prognosis. It has been shown that lung cancer patients with HIV progress faster in comparison to patients without HIV, and have a poor prognosis; however, there is no specific treatment protocol for lung cancer in patients with HIV. Case. The patient was a 55-year-old man who was diagnosed with advanced lung adenocarci-noma and infected with HIV. Platinum-based chemotherapy was administered, but the effect was poor, and docetaxel was started as the next treatment. He then showed prolonged myelosuppression, and his general condi-tion worsened, making it difficult to continue chemotherapy. Conclusion. We report a case of advanced lung cancer in a patient with HIV infection. It is hoped that standard chemotherapy for advanced lung cancer with HIV infection will be established.","PeriodicalId":35081,"journal":{"name":"Japanese Journal of Lung Cancer","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Case of Treatment-resistant Advanced Lung Cancer in a Patient with HIV Infection\",\"authors\":\"Ippei Miyamoto, Tetsuo Shimizu, Shunji Yokota, Yuji Yamakawa, Haruyasu Sakuranaka, K. Igei, N. Okamoto, Y. Gon\",\"doi\":\"10.2482/haigan.62.1033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"━━ Background. Antiretroviral therapy has been introduced to improve the prognosis of patients with human immunodeficiency virus (HIV) infection, and as a result, non-AIDS-defining cancer (NADC) may af-fect the prognosis. It has been shown that lung cancer patients with HIV progress faster in comparison to patients without HIV, and have a poor prognosis; however, there is no specific treatment protocol for lung cancer in patients with HIV. Case. The patient was a 55-year-old man who was diagnosed with advanced lung adenocarci-noma and infected with HIV. Platinum-based chemotherapy was administered, but the effect was poor, and docetaxel was started as the next treatment. He then showed prolonged myelosuppression, and his general condi-tion worsened, making it difficult to continue chemotherapy. Conclusion. We report a case of advanced lung cancer in a patient with HIV infection. It is hoped that standard chemotherapy for advanced lung cancer with HIV infection will be established.\",\"PeriodicalId\":35081,\"journal\":{\"name\":\"Japanese Journal of Lung Cancer\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Japanese Journal of Lung Cancer\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2482/haigan.62.1033\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Lung Cancer","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2482/haigan.62.1033","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
A Case of Treatment-resistant Advanced Lung Cancer in a Patient with HIV Infection
━━ Background. Antiretroviral therapy has been introduced to improve the prognosis of patients with human immunodeficiency virus (HIV) infection, and as a result, non-AIDS-defining cancer (NADC) may af-fect the prognosis. It has been shown that lung cancer patients with HIV progress faster in comparison to patients without HIV, and have a poor prognosis; however, there is no specific treatment protocol for lung cancer in patients with HIV. Case. The patient was a 55-year-old man who was diagnosed with advanced lung adenocarci-noma and infected with HIV. Platinum-based chemotherapy was administered, but the effect was poor, and docetaxel was started as the next treatment. He then showed prolonged myelosuppression, and his general condi-tion worsened, making it difficult to continue chemotherapy. Conclusion. We report a case of advanced lung cancer in a patient with HIV infection. It is hoped that standard chemotherapy for advanced lung cancer with HIV infection will be established.
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