年轻患者的炎症性成纤维细胞肿瘤和肝脓肿

Q4 Medicine
S. Grgic, Linda Soldo Čorić, Vesna Antunović Skelo, S. Kukić, H. B. Ivanković, Ž. Sulaver, Belma Gazibera
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引用次数: 0

摘要

简介:炎症性成纤维细胞瘤是一种罕见的肿瘤,最常见于年轻人,通常在30岁或以下,但最常见于6-10岁的儿童。它通常影响胃肠道和肺部,但也可能同时发生在几个地方。临床表现因受影响的身体系统而异,因此如果不进行手术摘除和病理分析,很难确定诊断。对大多数患者来说,完全手术切除是可以治愈的,累犯很少。肝脓肿更常见于有糖尿病、既往肝病病史的女性,而肉芽肿性疾病患者发生肝脓肿的可能性较小。在发展中国家,肝脓肿的死亡率为2-12%,由于开放式手术引流而增加。病例报告:我们介绍了一名35岁的患者,他于2018年8月和9月在莫斯塔尔大学医院和萨拉热窝大学医院传染病诊所、2018年12月在萨格勒布梅尔库尔临床医院外科诊所接受治疗。数据来自医疗文件。一名年轻、免疫功能强的患者因高烧、发冷和全身状况不佳而被送往医院,被诊断为多发性局灶性坏死病变,经鉴别诊断,很可能是肝脏和脾脏脓肿,高度怀疑为肝脏恶性肿瘤。进行了肝活检,病理学分析证实了IV和VI肝段多发性肝脓肿的诊断,以及IV肝段炎症性成纤维细胞瘤的诊断。经过8周的保守治疗,肝脓肿完全消退,2018年12月在萨格勒布的外科诊所。结论:多发性肝脓肿和肝肿瘤患者的治疗方法需要亚专家的经验和紧急的多学科诊断和治疗方法,以防止进一步的并发症和致命结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inflamatory fibroblast tumor and liver abscesses in the young patient
Introduction: Inflammatory fibroblast tumor is rare tumor that most often occurs in younger people, usually 30 years old or younger, but most commonly in children age 6-10 years. It usually affects gastrointestinal tract and the lungs but it can also occur in several places at the same time. Clinical manifestations vary depending of the affected system of the body so it is very difficult to determine diagnosis without surgical extirpation and patohistological analysis. Complete surgical resection is curative in most patients and recidivism is rare. Liver abscesses more common occur in females with risk factors and medical history of diabetes, previous liver disease and less likely in patients with granulomatous diseases. Liver abscesses mortality in developing countries is 2-12%, increasing due to open surgical drainage.Case report: We present a 35 years-old patient who was treated at the Clinic for Infectious Diseases University Hospital Mostar and University Hospital Sarajevo, Clinic for Infectious Diseases in August and September 2018 and Clinical Hospital Merkur, Zagreb Surgery Clinic in December 2018. Data was used from medical documentation. Young, immunocompetent patient who was addmited to a hospital following high fever, chills and poor general condition was diagnosed with multiple focal necrotic lesions, differential-diagnostically most likely liver and spleen abscesses with high suspicion of liver malignancy. Liver biopsy was performed and patohistological analysis confirmed the diagnosis of multiple liver abscesses in the IV and VI liver segment, and inflamatory fibroblast tumor in the IV liver segment. Eight weeks of conservative treatment resulted in a complete regression of liver abscesses and inflamatory fibroblast tumor was surgically extirpated at the Clinic Hospital Merkur, Surgery Clinic in the Zagreb in December 2018.Conclusion: An approach to a patient with a multiple liver abscesses and liver tumor requires sub-specialists experience and urgent multidisciplinary diagnostic and treatment approach to prevent further complications and deadly outcome. 
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Acta Medica Saliniana
Acta Medica Saliniana Medicine-Medicine (all)
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