T. Litovchenko, O. Sukhonosova, A. I. Ekzarkhova, S. Korenev, V. Salnikova, V. B. Olenich
{"title":"不同年龄段患者癫痫性肌阵挛发作的特点","authors":"T. Litovchenko, O. Sukhonosova, A. I. Ekzarkhova, S. Korenev, V. Salnikova, V. B. Olenich","doi":"10.37436/2308-5274-2021-4-11","DOIUrl":null,"url":null,"abstract":"The main manifestation of epilepsy is a seizure, the clinical embodiments of which depend on the location of the epileptic focus in brain, the pathways of excitation, brain maturity, and so on. Many neurological diseases, including epilepsy, are myoclonus, i.e. short−term involuntary contractions of single or groups of muscles in the torso and limbs. The prevalence of myoclonus in radically different options for predicting the diseases not only of the nervous system, but also of other organs and systems determines the relevance of this problem. In order to study, analyze and generalize modern approaches to epileptic myoclonus, its diagnosis as well as differential diagnoses, and also treatment at different ages for implementation into practical medicine, 62 children with epilepsy were examined. The results of the study show that myoclonic epileptic seizures are more common in young children. Such conditions were observed in most patients in the structure of idiopathic generalized epilepsy. In children of early age there are very frequent serial attacks which are combined with several other types of attacks: infantile spasms, tonic, clonic, atonic. Most patients had a drug−resistant type of disease. In adolescents the idiopathic forms prevailed. Myoclonic seizures could be combined with other generalized types of seizures. In this study, more than half of the patients had a drug−resistant course due to the encephalitic type of epilepsy. Almost half of the children managed to achieve stable remission for more than a year. Patients received levetiracetam, clonazepam in age doses as mono− and polytherapies. According to the results of the study, it was concluded that the correct diagnosis, timely treatment are the basic principles of management of the patients with myoclonic seizures.\n\nKey words: epilepsy, children, epileptic myoclonic seizures.","PeriodicalId":54933,"journal":{"name":"International Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"FEATURES OF EPILEPTIC MYOCLONIC SEIZURES IN PATIENTS AT DIFFERENT AGE PERIODS\",\"authors\":\"T. Litovchenko, O. Sukhonosova, A. I. Ekzarkhova, S. Korenev, V. Salnikova, V. B. Olenich\",\"doi\":\"10.37436/2308-5274-2021-4-11\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The main manifestation of epilepsy is a seizure, the clinical embodiments of which depend on the location of the epileptic focus in brain, the pathways of excitation, brain maturity, and so on. Many neurological diseases, including epilepsy, are myoclonus, i.e. short−term involuntary contractions of single or groups of muscles in the torso and limbs. The prevalence of myoclonus in radically different options for predicting the diseases not only of the nervous system, but also of other organs and systems determines the relevance of this problem. In order to study, analyze and generalize modern approaches to epileptic myoclonus, its diagnosis as well as differential diagnoses, and also treatment at different ages for implementation into practical medicine, 62 children with epilepsy were examined. The results of the study show that myoclonic epileptic seizures are more common in young children. Such conditions were observed in most patients in the structure of idiopathic generalized epilepsy. In children of early age there are very frequent serial attacks which are combined with several other types of attacks: infantile spasms, tonic, clonic, atonic. Most patients had a drug−resistant type of disease. In adolescents the idiopathic forms prevailed. Myoclonic seizures could be combined with other generalized types of seizures. In this study, more than half of the patients had a drug−resistant course due to the encephalitic type of epilepsy. Almost half of the children managed to achieve stable remission for more than a year. Patients received levetiracetam, clonazepam in age doses as mono− and polytherapies. 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FEATURES OF EPILEPTIC MYOCLONIC SEIZURES IN PATIENTS AT DIFFERENT AGE PERIODS
The main manifestation of epilepsy is a seizure, the clinical embodiments of which depend on the location of the epileptic focus in brain, the pathways of excitation, brain maturity, and so on. Many neurological diseases, including epilepsy, are myoclonus, i.e. short−term involuntary contractions of single or groups of muscles in the torso and limbs. The prevalence of myoclonus in radically different options for predicting the diseases not only of the nervous system, but also of other organs and systems determines the relevance of this problem. In order to study, analyze and generalize modern approaches to epileptic myoclonus, its diagnosis as well as differential diagnoses, and also treatment at different ages for implementation into practical medicine, 62 children with epilepsy were examined. The results of the study show that myoclonic epileptic seizures are more common in young children. Such conditions were observed in most patients in the structure of idiopathic generalized epilepsy. In children of early age there are very frequent serial attacks which are combined with several other types of attacks: infantile spasms, tonic, clonic, atonic. Most patients had a drug−resistant type of disease. In adolescents the idiopathic forms prevailed. Myoclonic seizures could be combined with other generalized types of seizures. In this study, more than half of the patients had a drug−resistant course due to the encephalitic type of epilepsy. Almost half of the children managed to achieve stable remission for more than a year. Patients received levetiracetam, clonazepam in age doses as mono− and polytherapies. According to the results of the study, it was concluded that the correct diagnosis, timely treatment are the basic principles of management of the patients with myoclonic seizures.
Key words: epilepsy, children, epileptic myoclonic seizures.
期刊介绍:
The International Medical Journal is intended to provide a multidisciplinary forum for the exchange of ideas and information among professionals concerned with medicine and related disciplines in the world. It is recognized that many other disciplines have an important contribution to make in furthering knowledge of the physical life and mental life and the Editors welcome relevant contributions from them.
The Editors and Publishers wish to encourage a dialogue among the experts from different countries whose diverse cultures afford interesting and challenging alternatives to existing theories and practices. Priority will therefore be given to articles which are oriented to an international perspective. The journal will publish reviews of high quality on contemporary issues, significant clinical studies, and conceptual contributions, as well as serve in the rapid dissemination of important and relevant research findings.
The International Medical Journal (IMJ) was first established in 1994.