不同年龄段患者癫痫性肌阵挛发作的特点

Q4 Medicine
T. Litovchenko, O. Sukhonosova, A. I. Ekzarkhova, S. Korenev, V. Salnikova, V. B. Olenich
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引用次数: 0

摘要

癫痫的主要表现为癫痫发作,其临床表现取决于癫痫灶在大脑中的位置、兴奋通路、大脑成熟度等。包括癫痫在内的许多神经系统疾病都是肌阵挛,即躯干和四肢单个或群肌肉的短期不自主收缩。肌阵挛在预测神经系统疾病以及其他器官和系统疾病的完全不同的选择中的流行程度决定了这个问题的相关性。为研究、分析和推广癫痫性肌阵挛的现代诊断方法、鉴别诊断方法和不同年龄阶段的治疗方法,并将其应用于医学实践,对62例癫痫患儿进行了临床检查。研究结果表明,肌阵挛性癫痫发作在幼儿中更为常见。这种情况在大多数特发性全身性癫痫患者的结构中观察到。在早期儿童中,有非常频繁的连环发作,并伴有其他几种类型的发作:婴儿痉挛,强直性,阵挛性,无张力性。大多数患者患有耐药型疾病。在青少年中以特发性形式为主。肌阵挛性发作可与其他全身性发作合并。在这项研究中,超过一半的患者由于脑病型癫痫而出现耐药性病程。几乎一半的儿童在一年多的时间里都能达到稳定的缓解。患者接受年龄剂量的左乙拉西坦、氯硝西泮单药和多药治疗。根据研究结果,得出正确诊断、及时治疗是治疗肌阵挛发作患者的基本原则。关键词:癫痫,儿童,癫痫性肌阵挛发作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
FEATURES OF EPILEPTIC MYOCLONIC SEIZURES IN PATIENTS AT DIFFERENT AGE PERIODS
The main manifestation of epilepsy is a seizure, the clinical embodiments of which depend on the location of the epileptic focus in brain, the pathways of excitation, brain maturity, and so on. Many neurological diseases, including epilepsy, are myoclonus, i.e. short−term involuntary contractions of single or groups of muscles in the torso and limbs. The prevalence of myoclonus in radically different options for predicting the diseases not only of the nervous system, but also of other organs and systems determines the relevance of this problem. In order to study, analyze and generalize modern approaches to epileptic myoclonus, its diagnosis as well as differential diagnoses, and also treatment at different ages for implementation into practical medicine, 62 children with epilepsy were examined. The results of the study show that myoclonic epileptic seizures are more common in young children. Such conditions were observed in most patients in the structure of idiopathic generalized epilepsy. In children of early age there are very frequent serial attacks which are combined with several other types of attacks: infantile spasms, tonic, clonic, atonic. Most patients had a drug−resistant type of disease. In adolescents the idiopathic forms prevailed. Myoclonic seizures could be combined with other generalized types of seizures. In this study, more than half of the patients had a drug−resistant course due to the encephalitic type of epilepsy. Almost half of the children managed to achieve stable remission for more than a year. Patients received levetiracetam, clonazepam in age doses as mono− and polytherapies. According to the results of the study, it was concluded that the correct diagnosis, timely treatment are the basic principles of management of the patients with myoclonic seizures. Key words: epilepsy, children, epileptic myoclonic seizures.
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来源期刊
International Medical Journal
International Medical Journal 医学-医学:内科
自引率
0.00%
发文量
21
审稿时长
4-8 weeks
期刊介绍: The International Medical Journal is intended to provide a multidisciplinary forum for the exchange of ideas and information among professionals concerned with medicine and related disciplines in the world. It is recognized that many other disciplines have an important contribution to make in furthering knowledge of the physical life and mental life and the Editors welcome relevant contributions from them. The Editors and Publishers wish to encourage a dialogue among the experts from different countries whose diverse cultures afford interesting and challenging alternatives to existing theories and practices. Priority will therefore be given to articles which are oriented to an international perspective. The journal will publish reviews of high quality on contemporary issues, significant clinical studies, and conceptual contributions, as well as serve in the rapid dissemination of important and relevant research findings. The International Medical Journal (IMJ) was first established in 1994.
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