五岁以下儿童死亡时间及危险因素的多层次建模

A. Argawu
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引用次数: 2

摘要

五岁以下儿童死亡率是一个国家儿童健康和整体发展的主要指标。撒哈拉以南非洲仍然是世界上5岁以下儿童死亡率最高的地区,每13名儿童中就有1名在5岁生日前死亡。2019年,五岁以下儿童死亡人数中有一半发生在五个国家:尼日利亚、印度、巴基斯坦、刚果民主共和国和埃塞俄比亚。在埃塞俄比亚,2016年埃塞俄比亚人口与健康调查(EDHS)报告显示,五岁以下儿童死亡率从2000年的每1000名活产166人下降到2019年的小型EDHS报告中的每1000例活产67人(下降率为60%)。然而,埃塞俄比亚在五岁以下儿童死亡率方面存在地区差异问题。因此,本研究的主要目的是模拟U5儿童死亡时间的多水平影响,并根据上一份完整报告(2016年EDHS)确定儿童死亡的风险因素。使用描述性统计、分层Cox比例风险回归和多水平参数生存模型对数据进行分析。在这项研究中,10331名儿童中有635人(6.1%)死于U5。总生存概率为0.93。通过拟合分层Cox比例风险回归和对数正态参数固定效应模型获得的结果:儿童性别、出生类型、出生顺序、出生时儿童的大小(体重)、母乳喂养的月份、U5和5个孩子的数量、家庭规模、财富指数、收听广播的频率、分娩地点、居住地,地理区域是U5儿童死亡或估计平均生存时间的重要因素。此外,发现U5儿童的高风险死亡与男性儿童、双胞胎儿童、≤6个月的母乳喂养儿童、家中儿童数量少、家庭规模小、儿童平均体重以下、贫困家庭儿童、私营卫生部门分娩的儿童、母亲不听广播的儿童、农村地区的儿童、,来自阿法尔州、索马里州和哈拉里州的儿童。在对数正态参数随机效应模型中,在U5儿童平均生存时间的区域和家庭集群水平之间观察到1.7和0.9的估计变化。研究人员建议,政府和其他相关机构应为孩子死亡风险高的母亲提供特殊支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multilevel Modelling of Under-Five Time to Death, and Risk Factors
Under-five mortality is a leading indicator of child health and overall development of a country. Sub-Saharan Africa remains the region with the highest under-5 mortality rate in the world, with 1 child in 13 dying before his or her fifth birthday. Half of all under-five deaths in 2019 occurred in just five countries: Nigeria, India, Pakistan, the Democratic Republic of the Congo, and Ethiopia. In Ethiopia, as the 2016 Ethiopia Demographic and Health Survey (EDHS) report showed that the under-five mortality declined from 166 deaths per 1,000 live births in 2000 to 67 deaths per 1,000 live births in 2019 mini EDHS report (60% decreasing rate). However, there are regional disparities problems on under-five children mortality in Ethiopia. Thus, the major purpose of this study was to model the multilevel effects of U5 child time to death, and to determine the risk factors for child’s death based on the last full report (2016 EDHS). The data were analysed using descriptive statistics, stratified Cox proportional hazards regression and multilevel parametric survival models. In the study, 635 (6.1%) U5 deaths have observed from 10,331 children. And, the overall probability of survival was 0.93. Results obtained by fitting both stratified Cox proportional hazards regression and lognormal parametric fixed-effect models: sex of child, type of birth, birth order, size (weight) of child at birth, months of breastfeeding, number of U5 and five children, family size, wealth index, frequency of listening radio, place of delivery place of residence, and geographical region were found to be significant factors for U5 children death or estimated mean survival time. Furthermore a high risk death of U5 children was found to be associated with male children, twined children, ≤ 6 months breastfeeding children, few number of children in the home, children from small family size, children average weight below, children from poor families, private health sectors delivered children, children from mothers didn’t not listen radio, children from rural areas, children from Afar, Somali and Harari regional states. In the lognormal parametric random effects model, 1.7 and 0.9 estimated variations were observed among regional and household cluster levels on U5 children mean survival times. The researchers recommended that governments, and other concerned bodies should give special supports for mothers whose children are at high risk of death.
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