Anchored Spacers Versus Standalone Cages in Two Levels Anterior Cervical Discectomy for Treatment of Degenerative Cervical Disc Disease; A Comparative Study

Background Data: Anterior cervical discectomy and fusion (ACDF) has been standard procedure in treatment of degenerative cervical disc disease. In order to reduce risks associated with traditional methods of anterior cervical discectomy with fusion a new zero profile cage with screws has been introduced and widely used.Purpose: To compare the clinical and radiological outcomes of two levels ACDF using stand-alone peek cage and zero profile anchored cage with screws.Study Design: Two groups of patients were enrolled in this study; Group A involving 30 consecutive patients that underwent two levels ACDF using standalone peek cages, and Group B including 30 patients that underwent two levels ACDF with zero-profile anchored cage with screws.Patients and Methods: Both surgical groups were assessed clinically involving neck and arm pain Visual Analogue Score (VAS), neck disability index and Nurick score. Radiological evaluation involved the changes in vertebral heights (VH), both segmental (Cobb-s) and global (Cobb-c) Cobb angle and fusion rates via plain X-ray cervical spine that was done pre-operative, immediate post-operative and at 24 months post-operative.Results: The neck disability index and the Nurick score together with both VAS for neck and arm pain were significantly improved after surgery with no statistical difference between both groups. All patients in both groups showed satisfactory fusion rates except two patients in Group A. Both groups showed early marked increase in the VH followed later by cage subsidence that was significantly higher in Group A patients. In both groups; Cobb-c, and Cobb-s angles were significantly increased in the immediate postoperative compared to the preoperative measures. Terminal measures for both Cobb-c and Cobb-s, at 24 months follow up images, in both groups worsened but to a statistically significant lesser extent in Group B compared to Group A.Conclusion: The zero-profile anchored cage with screws compared to stand-alone peek cage was effective treatment for cervical disc disorders in two levels cervical discectomy and fusion and their results showed better result regarding the incidence of cage subsidence and maintaining cervical lordosis. (2018ESJ169)