Combined Training Reduces Redox and Inflammatory Biomarkers and Improves General-Social Health in Elderly Men

Background: Increased inflammation and oxidative stress are the main causes of many common diseases of old age. Objectives: The aim of the present study was to evaluate the effects of combined training on inflammatory and oxidative markers and the general-social health of overweight older male adults. Methods: In this quasi-experimental study, 40 overweight older male adults with an age range of 60 - 75 years were purposefully selected and randomly divided into two training and control groups. The training program included aerobic, resistance, and balance training for eight weeks and three days a week. Study variables were measured 48 hours before and after the intervention. The statistical analysis of the data was done by two-way repeated measure analysis of variance and Tukey's post hoc tests at a significance level of P ≤ 0.05. Results: After eight weeks of combined training, levels of TNF-α (P ≤ 0.01), hs-CRP (P ≤ 0.03), and MDA (P ≤ 0.01), the mass of fat (P ≤ 0.04) decreased, while the level of superoxide dismutase (P ≤ 0.01) and the score of social health (P ≤ 0.01) increased significantly. Conclusions: It seems that combined training in the elderly is a suitable option for modulating and regulating inflammatory and oxidative biomarkers and improving general social health.