颈动脉内膜切除术患者血清过氧化物酶体多糖-1的研究——简短报告

IF 0.4 Q4 PERIPHERAL VASCULAR DISEASE

Acta Angiologica Pub Date : 2021-10-21 DOI:10.5603/aa.2021.0009

M. Iłżecki, M. Feldo, A. Bogucka-Kocka, D. Zalewski, Paulina Chmiel, Shavn Dave, J. Iłżecka

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引用次数: 0

摘要

引言：颈内动脉内膜切除术（CEA）在预防缺血性脑卒中中起着重要作用；然而，这种外科手术可能会引起神经系统并发症。本研究的目的是评估接受CEA治疗的患者血清氧化应激标志物过氧化物酶体阿霉素-1（PRDX1）水平的变化。材料和方法：24名因颈内动脉严重狭窄而接受动脉内膜切除术的患者参与了这项研究。CEA前采集检测用血，术后采集两次。用ELISA法测定PRDX1。结果：采血时间不影响PRDX1水平（p>0.05）。男性组和女性组血清PRDX1含量与患者年龄无统计学显著差异（p>0.05）；结论：PRDX1不能作为CEA后神经系统并发症的标志物。

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Serum peroxiredoxin-1 in patients undergoing carotid endarterectomy – short report

Introduction: Endarterectomy of the internal carotid artery (CEA) plays an important role in the prevention of cerebral ischemic stroke; however, this surgical procedure may cause neurological complications. The aim of this study was to evaluate changes in serum levels of the oxidative stress marker peroxiredoxin-1 (PRDX1) in patients undergoing CEA. Material and methods: Twenty-four patients undergoing endarterectomy for critical stenosis of the internal carotid artery participated in the study. Blood for testing was collected before CEA and twice after surgery. PRDX1 was determined by ELISA. Results: The timing of blood sampling did not affect PRDX1 levels (p > 0.05). There was no statistically significant difference in serum PRDX1 levels between male and female groups and depending on the age of the patients (p > 0.05). Conclusion: PRDX1 cannot be considered as a marker of neurological complications after CEA.

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来源期刊

Acta Angiologica PERIPHERAL VASCULAR DISEASE-

CiteScore

0.30

自引率

0.00%

发文量

审稿时长

26 weeks

期刊介绍： Acta Angiologica is a bilingual (Polish/English) quarterly for angiologists and vascular surgeons as well as for other doctors interested in vascular disorders. Original papers, reviews, case reports and letters submitted by authors from different countries, concerning physiology, pathology, presentation, diagnostics and treatment of vascular system, are published. Thorough contents of Acta Angiologica provide valuable information about modern diagnostic and therapeutic issues as well as advances in basic sciences and pharmacology.