用于2022年猴痘病毒全球爆发基因组分析的网络工具。

IF 0.1 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Investigacion clinica Pub Date : 2023-03-03 DOI:10.54817/ic.v64n1a06

Z. Moros, C. Loureiro, R. Jaspe, Y. Sulbarán, M. Delgado, O. C. Aristimuño, Christopher Franco, D. Garzaro, Mariajosé Rodríguez, H. Rangel, F. Liprandi, F. Pujol, J. L. Zambrano

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引用次数: 0

摘要

互联网上可用于收集和共享信息以及进行基因组序列分析的资源和平台，使密切跟踪新冠病毒的演变成为可能。然而，目前世界上猴痘疫情使我们重新认识到需要利用这些资源来评估这次疫情的程度。这项工作的目的是利用网络上提供的各种工具，分析迄今为止在基因组数据库GISAID EpiPox™中呈现的信息。结果表明，此次猴痘暴发为MPXVⅱB.1分支和亚谱系，主要来自欧洲和美洲大陆的男性患者。在目前的情况下，获取基因组序列、流行病学信息和科学界可用的工具对全球公共卫生至关重要，以便跟踪病原体的演变。

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Web-tools for the genomic analysis of the 2022 Monkeypox virus global outbreak.

The resources and platforms available on the internet for collect-ing and sharing information and performing genomic sequence analysis have made it possible to follow closely the evolution the evolution of SARS-CoV-2. However, the current monkeypox outbreak in the world brings us back to the need to use these resources to appraise the extent of this outbreak. The ob-jective of this work was an analysis of the information presented so far in the genomic database GISAID EpiPox™, using various tools available on the web. The results indicate that the monkeypox outbreak is referred as MPXV clade II B.1 lineage and sub-lineages, isolated from male patients mainly from the Euro-pean and American continents. In the current scenario, the access to genomic sequences, epidemiological information, and tools available to the scientific community is of great importance for global public health in order to follow the evolution of pathogens.

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