慢性约束应激对雄性Sprague-Dawley大鼠体重的影响

Journal of Rawalpindi Medical College Pub Date : 2023-04-02 DOI:10.37939/jrmc.v27i1.1848

Sadia Moazzam, I. Mughal, Noor-ul-ain Irfan, Ilqa Attique, Fareeha Zaheer, Asma Irfan

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引用次数: 0

摘要

背景：压力会影响体重和食物摄入，但其核心机制尚不清楚。研究设计：实验材料和方法：本研究在伊斯兰堡国家卫生研究所（NIH）进行。使用60只雄性Sprague-Dawley大鼠（平均体重250±50克），分为2组。每组30只大鼠。第一组为对照组。第二组暴露于慢性应激。结果：不同组的体重增加比较表明，与对照组相比，暴露于慢性应激的大鼠的体重增加显著减少。结论：慢性束缚应激对体重有不利影响。

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Effect of chronic restraint stress on body weight of male Sprague Dawley rats

Background: Stress disturbs body weight and food intake, but the core mechanisms are not well understood. Study design: Experimental Materials and Methods: The study was conducted in National Institute of Health (NIH), Islamabad Sixty male Sprague Dawley rats (mean wt 250 ± 50 grams) were used and divided into 2 groups. Each group comprised of 30 rats. Group I was taken as control. Group II was exposed to chronic stress. Results: The comparison of weight gain by the different groups disclosed that there was a significant decrease in weight gain of rats exposed to the chronic stress as compared to control group. Conclusion: Chronic restraint stress has a detrimental effect on body weight.

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Journal of Rawalpindi Medical College

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0.00%

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审稿时长

24 weeks