利用流体结构相互作用评价二尖瓣返流

Atefe Rajaei, K. Hassani, A. T. Golpaygani
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引用次数: 0

摘要

在本研究中,采用三维流体-结构相互作用方法对二尖瓣反流进行了研究。流体-结构相互作用建模技术在生物工程科学中有着广泛的应用。然而,尽管取得了所有这些进展,但在心血管并发症领域的此类研究仍然有限,似乎有必要进行进一步的研究。使用这些方法,可以获得结果,而不需要复杂的实验室设备和系统,也不需要花费大量的时间和金钱,并且只需要对二尖瓣的行为进行建模。在这项研究中,我们试图使用数值求解软件模拟血流的流体动力学及其与二尖瓣回流的相互作用,并用可用的实验室结果进行验证。对导致回流的二尖瓣完全关闭进行了三维数值模拟。制作二尖瓣、左心房和左心室。这些图像由240个切片组成,由多层计算机断层扫描机拍摄,在超音速Geomagic软件中转换为体积,然后输入ANSYS软件。对该项目进行了流体-结构相互作用分析,并报告了结果。对结果的评估和比较表明,正常状态下瓣膜壁上的von Mises应力和剪切应力高于所有其他状态,而正常状态下的血流速度和压力低于其他状态。最大剪切应力、von Mises应力、血流速度和压力,以及两个瓣叶之间的较大距离,是影响二尖瓣功能异常的主要参数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Mitral Regurgitation Using Fluid Structure Interaction
In this study, mitral regurgitation was investigated using fluid-structure interaction method in 3 dimensions. The fluid-structure interaction modeling technique has been widely used for a wide range of applications in bioengineering sciences. However, despite all these advances, such studies in the field of cardiovascular complications are still limited, and the need for further research and studies seems necessary. Using these methods, the results can be obtained without the need for complex laboratory devices and systems and without spending a lot of time and money and only by modeling the behavior of the mitral valve. In this study, we tried to simulate the hydrodynamics of blood flow and its interaction with the return flow through the mitral valve using numerical solution software and validate it with the available laboratory results. A 3-dimensional numerical simulation was performed for the complete closure of the mitral valve leading to a return flow. Mitral valve, left atrium, and left ventricle were made. These images, consisting of 240 slices, were taken by a multislice computed tomography scan machine, converted to volume in supersonic Geomagic software, and then entered in ANSYS software. Fluid-structure interaction analysis was performed on the project, and the results were reported. Evaluation and comparison of the results show that von Mises stress and shear stress on the valve wall are higher in the normal state than all other conditions, whereas the velocity and pressure of blood flow in the normal state are less than other states. The highest shear stress, von Mises stress, blood flow velocity, and pressure, as well as the greater distance between the 2 leaflets, are the main parameters that affect the abnormities of mitral valve function.
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