cyp17基因多态性与山羊生产和繁殖性能的关系

Wala'a Mohammed Abdullah, Wafa'a Ismail Abraheem, Ali Najm Abdullah
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引用次数: 0

摘要

这项研究是在伊拉克农业部农业研究办公室反刍动物研究站进行的,目的是检测当地山羊和沙米山羊的CYP17基因多态性,并确定SNPs是否与一些生产和繁殖性状有关,如总产奶量(TMY)及其组分,除了生殖特征,包括产仔数和生育能力。利用DNA测序技术在804bp的研究片段中发现了一个重要的单核苷酸多态性(SNPs)(G2276C),包括外显子2、内含子2和外显子3部分。结果表明,两个品种的基因型百分比和等位基因频率分布存在高度差异。结果表明,该SNPs的多态性与乳脂百分比和产仔数之间存在显著关系,其中本地山羊的乳脂百分比和产仔数中,异基因型GC超过GG基因型,而野生基因型GG在沙米山羊的乳脂率上有显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ASSOCIATION OF CYP17 GENE POLYMORPHISME IN PRODUCTIVE AND REPRODUCTIVE PERFORMANCE IN GOAT
This study was conducted in the Ruminants Research Station, Office of Agricultural Research/ Ministry of Agriculture- Iraq to detect CYP17 gene polymorphisms in Local and Shami goat, as well as to establish if SNPs could be associated with some productive and reproductive traits such as total milk yield (TMY) and its components, in addition to reproductive traits which included litter size and fertility. An important single nucleotide polymorphisms (SNPs) (G2276C) were found in the studying fragment (804 bp), which include Exon2, intron2, and partial of Exon3 by using DNA sequencing technique, two genotypes were produced wild GG and GC in both breeds. Results proposed a highly differences among distribution of genotypes percentage and allele frequencies in both breeds, Results stated a significant relationship between polymorphisms of this SNPs and milk fat percentage and litter size, where hetero genotype GC exceeded GG genotype in milk fat percentage and litter size in Local goat, whereas wild genotype GG distinguished in milk fat percentage in Shami goat.
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