糖尿病和高血压在良性前列腺增生形成中的影响作用

R. Shah, R. Tamang
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引用次数: 1

摘要

背景:良性前列腺增生被认为是前列腺组织的非恶性生长,是男性最常见的良性肿瘤,其发病率与年龄有关。在50岁以上的男性中,它是第四大流行疾病。本研究旨在探讨良性前列腺增生与糖尿病和/或高血压的关系,为良性前列腺增生、高血压和糖尿病的治疗提供新的思路。材料与方法:纳入2018年5月至2019年2月经机构审查委员会批准在泌尿外科门诊诊断为前列腺良性肿大的540例患者,对照组270例。排除有前列腺癌病史、神经源性膀胱癌、前列腺手术干预史、不愿参加研究的患者。结果:病例与对照组年龄均为41 ~ 94岁。14.63%的病例和11.85%的对照组存在糖尿病。前列腺增生与糖尿病呈正相关(p = 0.27)。高血压发生率为37.96%,对照组为29.63% (p = 0.019)。糖尿病和高血压发生率为56.48%,对照组为43.33% (p = 0.000)。结论:研究提示良性前列腺增生与糖尿病、高血压有关,为良性前列腺增生的治疗提供了新的思路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Influencing Role of Diabetes Mellitus and Hypertension in the Establishment of Benign Prostatic Hyperplasia
Background: Benign prostatic hyperplasia is regarded as non-malignant growth of prostatic tissueIt is the most common benign tumor in men, and the incidence is age related. In men aged more than 50 years, it is the fourth most prevalent disease. This study aim to determine the association of benign prostatic hyperplasia with diabetes mellitus and/or hypertension and this may help to bring out new dimensions in management of benign prostatic hyperplasia, hypertension and diabetes mellitus. Materials and Methods: Five hundred forty patients, diagnosed as benign enlargement of prostate with control group 270 at Urology out patient door between May 2018 to February 2019 with approval of Institutional review committee, were included. Patient with history of prostate cancer, neurogenic bladder, those who had undergone surgical intervention for prostate, not willing to take part in study were excluded. Results: Age range in cases and control were from 41–94 years. Diabetes was present in 14.63% of cases and 11.85% of controls. The positive association was established between prostatic hyperplasia and Diabetes (P-0.27). Hypertension was present in 37.96% of cases and 29.63% of controls (P-0.019). Diabetes and Hypertension were present in 56.48% in cases and 43.33% in control (P-0.000). Conclusion: Study suggests that benign prostatic hyperplasia is associated with diabetes mellitus and hypertension and may help to bring out new dimensions in management of benign prostatic hyperplasia.
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