{"title":"马来西亚人群根治性肾切除术后新的基线肾功能计算器的可靠性和有效性","authors":"Chin Ooi, Y. Wong, S. Thevarajah","doi":"10.4103/uros.uros_140_21","DOIUrl":null,"url":null,"abstract":"Purpose: This study aimed to determine the reliability and validity of a new baseline renal function calculator after radical nephrectomy in Malaysian patients. Materials and Methods: This study retrospectively collected data on patients' demographics, tumor characteristics, and baseline estimated glomerular filtration rate (eGFR) during radical nephrectomy from a single urology center from 2015 to 2020. The predicted eGFR was determined using a calculator. Predicted eGFR was validated by performing simple linear regression and Pearson coefficient correlations; reliability was determined by calculating Shrout and Fleiss's intraclass correlation coefficients. Results: Fifty-two patients (mean age, 57.5 years) were enrolled in this study. Thirty-seven (71.2%) patients were men, and 15 (28.8%) had diabetes. Most of the patients (90.2%) had a baseline eGFR of >60 mL/min/1.73 m2. The mean preoperative eGFR was 85.33 mL/min/1.73 m2, whereas the mean postoperative eGFR was 59.88 mL/min/1.73 m2. Simple linear regression analysis resulted in an R2 value of 0.700. The predicted eGFR was significantly correlated with the actual eGFR 6 months after radical nephrectomy (r = 0.837, P < 0.0001). The intraclass correlation coefficient value of 0.83 indicated good reliability of the formula. Conclusion: Our new validated and reliable baseline renal function calculator can provide easy and rapid prediction of renal function in patients scheduled for radical nephrectomy in a sample Malaysian population.","PeriodicalId":23449,"journal":{"name":"Urological Science","volume":"33 1","pages":"82 - 85"},"PeriodicalIF":0.8000,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reliability and validity of a new baseline renal function calculator after radical nephrectomy in a Malaysian population\",\"authors\":\"Chin Ooi, Y. Wong, S. Thevarajah\",\"doi\":\"10.4103/uros.uros_140_21\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose: This study aimed to determine the reliability and validity of a new baseline renal function calculator after radical nephrectomy in Malaysian patients. Materials and Methods: This study retrospectively collected data on patients' demographics, tumor characteristics, and baseline estimated glomerular filtration rate (eGFR) during radical nephrectomy from a single urology center from 2015 to 2020. The predicted eGFR was determined using a calculator. Predicted eGFR was validated by performing simple linear regression and Pearson coefficient correlations; reliability was determined by calculating Shrout and Fleiss's intraclass correlation coefficients. Results: Fifty-two patients (mean age, 57.5 years) were enrolled in this study. Thirty-seven (71.2%) patients were men, and 15 (28.8%) had diabetes. Most of the patients (90.2%) had a baseline eGFR of >60 mL/min/1.73 m2. The mean preoperative eGFR was 85.33 mL/min/1.73 m2, whereas the mean postoperative eGFR was 59.88 mL/min/1.73 m2. Simple linear regression analysis resulted in an R2 value of 0.700. The predicted eGFR was significantly correlated with the actual eGFR 6 months after radical nephrectomy (r = 0.837, P < 0.0001). The intraclass correlation coefficient value of 0.83 indicated good reliability of the formula. Conclusion: Our new validated and reliable baseline renal function calculator can provide easy and rapid prediction of renal function in patients scheduled for radical nephrectomy in a sample Malaysian population.\",\"PeriodicalId\":23449,\"journal\":{\"name\":\"Urological Science\",\"volume\":\"33 1\",\"pages\":\"82 - 85\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2022-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urological Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/uros.uros_140_21\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urological Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/uros.uros_140_21","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Reliability and validity of a new baseline renal function calculator after radical nephrectomy in a Malaysian population
Purpose: This study aimed to determine the reliability and validity of a new baseline renal function calculator after radical nephrectomy in Malaysian patients. Materials and Methods: This study retrospectively collected data on patients' demographics, tumor characteristics, and baseline estimated glomerular filtration rate (eGFR) during radical nephrectomy from a single urology center from 2015 to 2020. The predicted eGFR was determined using a calculator. Predicted eGFR was validated by performing simple linear regression and Pearson coefficient correlations; reliability was determined by calculating Shrout and Fleiss's intraclass correlation coefficients. Results: Fifty-two patients (mean age, 57.5 years) were enrolled in this study. Thirty-seven (71.2%) patients were men, and 15 (28.8%) had diabetes. Most of the patients (90.2%) had a baseline eGFR of >60 mL/min/1.73 m2. The mean preoperative eGFR was 85.33 mL/min/1.73 m2, whereas the mean postoperative eGFR was 59.88 mL/min/1.73 m2. Simple linear regression analysis resulted in an R2 value of 0.700. The predicted eGFR was significantly correlated with the actual eGFR 6 months after radical nephrectomy (r = 0.837, P < 0.0001). The intraclass correlation coefficient value of 0.83 indicated good reliability of the formula. Conclusion: Our new validated and reliable baseline renal function calculator can provide easy and rapid prediction of renal function in patients scheduled for radical nephrectomy in a sample Malaysian population.