{"title":"色素性干皮病——眼睑和结膜两种不同眼部肿瘤的诊断和治疗","authors":"Hoehr Gc, Vesanterä Fr, Biselli Lg, Selegatto Lt, Batalha Cp, Alves Lp, Sobrinho Mva, Pereira Ic","doi":"10.4172/2324-8599.1000220","DOIUrl":null,"url":null,"abstract":"Xeroderma Pigmentosum is an autosomal recessive disease caused by alterations in the DNA repairing gene. The clinical manifestation involves extreme sensitivity to ultraviolet radiation and progressive effects in sun exposed areas (skin, mucosa and ocular surface) such as inflammation, sunburn, pigment changes and neoplasia. This disease may be associated with ocular findings such as dry eye syndrome, photophobia, blepharospasm and a number of corneal diseases such as ulceration, perforation and tumors. In this paper, we report the case of a patient with Xeroderma Pigmentosum, accompanied by ocular manifestations and treatment.","PeriodicalId":89944,"journal":{"name":"International Journal of Ophthalmic Pathology","volume":" ","pages":"1-3"},"PeriodicalIF":0.0000,"publicationDate":"2018-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Xeroderma Pigmentosum- Diagnosis and Treatment of Two Different Ocular Tumors in Eyelid and Conjunctiva\",\"authors\":\"Hoehr Gc, Vesanterä Fr, Biselli Lg, Selegatto Lt, Batalha Cp, Alves Lp, Sobrinho Mva, Pereira Ic\",\"doi\":\"10.4172/2324-8599.1000220\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Xeroderma Pigmentosum is an autosomal recessive disease caused by alterations in the DNA repairing gene. The clinical manifestation involves extreme sensitivity to ultraviolet radiation and progressive effects in sun exposed areas (skin, mucosa and ocular surface) such as inflammation, sunburn, pigment changes and neoplasia. This disease may be associated with ocular findings such as dry eye syndrome, photophobia, blepharospasm and a number of corneal diseases such as ulceration, perforation and tumors. In this paper, we report the case of a patient with Xeroderma Pigmentosum, accompanied by ocular manifestations and treatment.\",\"PeriodicalId\":89944,\"journal\":{\"name\":\"International Journal of Ophthalmic Pathology\",\"volume\":\" \",\"pages\":\"1-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-08-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Ophthalmic Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2324-8599.1000220\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Ophthalmic Pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2324-8599.1000220","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Xeroderma Pigmentosum- Diagnosis and Treatment of Two Different Ocular Tumors in Eyelid and Conjunctiva
Xeroderma Pigmentosum is an autosomal recessive disease caused by alterations in the DNA repairing gene. The clinical manifestation involves extreme sensitivity to ultraviolet radiation and progressive effects in sun exposed areas (skin, mucosa and ocular surface) such as inflammation, sunburn, pigment changes and neoplasia. This disease may be associated with ocular findings such as dry eye syndrome, photophobia, blepharospasm and a number of corneal diseases such as ulceration, perforation and tumors. In this paper, we report the case of a patient with Xeroderma Pigmentosum, accompanied by ocular manifestations and treatment.