2型糖尿病患者甲状腺激素与内脏脂肪面积的关系

Q4 Medicine

中华内分泌代谢杂志 Pub Date : 2020-02-25 DOI:10.3760/CMA.J.ISSN.1000-6699.2020.02.005

Yong Jin, Ye Zhou, Xuepeng Wang, Shuqin Chen, Yan-Shu Chen, Jing-jia Yu, Miao Xu, Yuchen Tang, Li Li

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引用次数: 1

摘要

目的探讨2型糖尿病患者甲状腺激素与内脏脂肪面积（VFA）的关系。方法纳入2018年3月至2019年7月通过宁波市第一医院进入国家代谢管理中心（MMC）的729例2型糖尿病患者。进行血液测试以评估他们的甲状腺激素和生化指标。通过生物电阻抗分析获得VFA和皮下脂肪面积（SFA）。统计数据随后通过Spearman相关分析和多元线性回归进行分析。结果Spearman相关分析显示，VFA与T3、FT3呈正相关（r分别为0.225和0.211，P＜0.05），多元线性回归分析显示VFA与FT4和FT3独立相关（P＜0.01），FT4增加1pmol/L与VFA增加1.759cm2相关，FT3增加1pmmol/L与VFA减少3.256cm2相关。结论2型糖尿病患者VFA与FT3、FT4有关。关键词：内脏脂肪区；甲状腺激素；2型糖尿病；代谢管理中心

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Association between thyroid hormones and visceral fat area in the patients with type 2 diabetes

Objective To explore the association between thyroid hormones and visceral fat area(VFA) in the patients with type 2 diabetes. Methods A total of 729 patients with type 2 diabetes, who joined National Metabolic Management Center(MMC) through Ningbo First Hospital from March, 2018 to July, 2019, were enrolled in this study. Blood tests were taken to assess their thyroid hormones and biochemical indexes. VFA and subcutaneous fat area(SFA) were obtained through bioelectrical impedance analysis. Statistics were later analyzed by Spearman correlation analysis and multivariate linear regression. Results Spearman correlation analysis showed that VFA were positively correlated with T3、FT3(r=0.225 and 0.211, P 0.05). Multivariate linear regression analysis indicated that VFA was independently correlated with FT4 and FT3(P<0.01). An increment of 1 pmol/L in FT4 was associated with 1.759 cm2 increase in VFA, and increment of 1 pmol/L in FT3 was associated with 3.256 cm2 decrease in VFA. Conclusion VFA in patients with type 2 diabetes are correlated with FT3 and FT4. Key words: Visceral fat area; Thyroid hormones; Diabetes mellitus, type 2; Metabolic Management Center

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来源期刊

中华内分泌代谢杂志 Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

0.60

自引率

0.00%

发文量

7243

期刊介绍： The Chinese Journal of Endocrinology and Metabolism was founded in July 1985. It is a senior academic journal in the field of endocrinology and metabolism sponsored by the Chinese Medical Association. The journal aims to be the "Chinese broadcaster of new knowledge on endocrinology and metabolism worldwide". It reports leading scientific research results and clinical diagnosis and treatment experience in endocrinology and metabolism and related fields, as well as basic theoretical research that has a guiding role in endocrinology and metabolism clinics and is closely integrated with clinics. The journal is a core journal of Chinese science and technology (a statistical source journal of Chinese science and technology papers), and is included in Chinese and foreign statistical source journal databases such as the Chinese Science and Technology Papers and Citation Database, Chemical Abstracts, and Scopus.