头颈部恶性肿瘤侵袭周围神经的临床诊断与治疗

中华放射肿瘤学杂志 Pub Date : 2020-02-15 DOI:10.3760/CMA.J.ISSN.1004-4221.2020.02.015

Zekun Wang

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引用次数: 0

摘要

神经周围浸润是肿瘤通过神经播散和转移的一种独特的生物学行为，与肿瘤的复发、转移和预后密切相关。随着研究的不断深入，神经周围侵犯的临床意义已被广泛认识。然而，由于头颈部肿瘤的发病率较低，且不同解剖部位和病理类型对神经周围侵袭的发生率不同，目前仍缺乏高水平的循证医学证据。目前，神经周围浸润的病理机制尚未明确。对于神经周围浸润没有特殊的治疗方法。因此，头颈部肿瘤侵袭周围神经的治疗对临床医生来说是一个巨大的挑战。本文就头颈部恶性肿瘤侵袭周围神经的临床诊断和治疗现状作一综述。关键词:头颈部肿瘤;围神经的入侵;诊断与治疗

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Clinical diagnosis and treatment of perineural invasion of head and neck malignant tumors

Perineural invasion is a unique biological behavior of tumors via nerve dissemination and metastasis, which is intimately correlated with the recurrence, metastasis and prognosis. With the deepening research, the clinical significance of perineural invasion has been widely recognized. However, due to the low incidence of head and neck neoplasms and the varying incidence of perineural invasion in different anatomical sites and pathological types, high-level evidence-based medical evidence is still lacking. Currently, the pathological mechanism of perineural invasion has not been clearly clarified. No specific treatment has been available for perineural invasion. Therefore, the treatment of perineural invasion of head and neck tumors is an enormous challenge for clinicians. In this article, the current status of clinical diagnosis and treatment of perineural invasion in head and neck malignancies was reviewed. Key words: Head and neck neoplasm; Perineural invasion; Diagnosis and treatment

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来源期刊

中华放射肿瘤学杂志

自引率

0.00%

发文量

6375

期刊介绍： The Chinese Journal of Radiation Oncology is a national academic journal sponsored by the Chinese Medical Association. It was founded in 1992 and the title was written by Chen Minzhang, the former Minister of Health. Its predecessor was the Chinese Journal of Radiation Oncology, which was founded in 1987. The journal is an authoritative journal in the field of radiation oncology in my country. It focuses on clinical tumor radiotherapy, tumor radiation physics, tumor radiation biology, and thermal therapy. Its main readers are middle and senior clinical doctors and scientific researchers. It is now a monthly journal with a large 16-page format and 80 pages of text. For many years, it has adhered to the principle of combining theory with practice and combining improvement with popularization. It now has columns such as monographs, head and neck tumors (monographs), chest tumors (monographs), abdominal tumors (monographs), physics, technology, biology (monographs), reviews, and investigations and research.